Breakthrough change

B) If they detect vapor or gas breakthrough, changes in breathing resistance, or leakage of... 

If an employee does detect vapor or gas breakthrough, changes in breathing resistance, or leakage of the facepiece, you need to investigate the situation and replace or repair the respirator before allowing the employee to retrum to work. 

Watson, G. H. (1994). Business systems engineering managing breakthrough changes for productivity and profit. New York, Chichester, Brisbane, Toronto, Singapore Wiley. 

The company must ensure that all employees leave the respirator use area to wash their faces and respirator fece pieees as neeessary to prevent eye or skin irritation associated with respirator use. If they detect vapor or gas breakthrough, changes in breathing resistanee, or leakage of the face piece, they must leave the area as quickly as possible. They must also leave the area to replace the respirator or the filter, cartridge, or canister elements. 

Breakthrough The first appearance in the solution flowing from an ion-ex- change imit of unabsorbed ions similar to those which are depleting the activity of the resin bed. Breakthrough is an indication that regeneration of the resin is necessary. 

Breakthrough bleeding, spotting, change in menstrual flow, amenorrhea, rash with or without pruritus, acne, fluid retention, edema, increase or decrease in weight, sudden, partial, or complete loss of vision, migraine, nausea... 

Although MIL-47, and especially MIL-53(A1), had been found on many occasions to dynamically respond to adsorption of particular compounds, referred to as breathing [35] in the literature, in these liquid phase conditions, only minor changes of the lattice parameters have been observed. A study of xylene separations in vapor phase on MIL-5 3(A1) shows that breathing profoundly influences the shape of the obtained breakthrough profiles as a function of adsorbate concentration [97]. 

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