Bovine lens

Garner, W.H., Gamer, M.H. and Spector, A. (1983). H2O2 induced uncoupling of bovine lens Na, K -ATPase. Proc. Natl Acad. Sci. USA 80, 2044-2048. 

Udupa, P.E., and Sharma, K.K. (2005) Effect of oxidized betaB3-crystallin peptide (152-166) on thermal aggregation of bovine lens gamma-crystallins identification of peptide interacting sites. Exp. Eye. Res. 80(2), 185-196. 

Gorin, M. B., Yancey, S. B., Cline, J., Revel, J. P. and Horwitz, J. (1984). The major intrinsic protein (MIP) of the bovine lens fiber membrane characterization and structure based on cDNA cloning, Cell, 39, 49-59. 

Type IV collagen subtype [ctl(IV)]2Q 2(IV) from bovine lens capsule forms a fine meshwork structure containing many branches with about 20 nm between the branching points. There are three types of supramolecular assembly of type IV collagen molecules dimer formation (with six polypeptide chains) at the C-terminal NCI domain, the association of four molecules (12 chains) in a 30 nm tetramer formation at the N-terminal 7S domain, and lateral interaction at the collagenous domain (Figure 5(a)). ° ... 

Recently, the crystal structure of the NCI domains of two molecules, in hexamer form, was analyzed by two different groups using either human placenta or bovine lens capsule. " A unique nonreducible but labile cross-link between Met and Lys/Hyl was found (Figure 5(b)). ... 

Pyrrolo[2,3-c]carbazole alkaloids (see Schemes 2.70-2.72) isolated from the dark green marine sponge, Dictyodendrilla sp., showed inhibitory activity against bovine lens aldose reductase catalyzing the reduction of aldoses to polyols which, on accumulation in cells, may result in diabetes. These alkaloids could provide prevention from such ailments (250). 

Baker, M.E. Saier, M.H. (1990). A common ancestor for bovine lens fiber major intrinsic protein, soybean nodulin-26 protein, and E. coli glycerol facilitator. Cell 60, 185-6. 

Incubation of D-xylose with an aqueous solution of bovine lens protein gave both xylitol and xylonic acid. Studies of the reaction under a variety of conditions suggest that both the reduction and oxidation reactions are protein (possibly enzyme) catalyzed and appear to be unique to lens... 

E. Yinan Li and M. S. Feather, The conversion of D-xylose to xylitol and D-xylonic acid by a bovine lens preparation, J. Carbohydr. Chem., 13 (1994) 499-505. 

Several thieno[3,2-d]pyrimidine-2,4-diones 267 were evaluated in vitro for their ability to inhibit enzymatic activity on partially purified bovine lens aldose reductase. A high level of in vitro activity was demonstrated (ICjo 10"6 to 4 x 10 8 M) (91JMC1492 93MI1). 

N Strater, WN Lipscomb (1995) Two-metal ion mechanism of bovine lens leucine aminopeptidase active site solvent structure and binding mode of L-leucinal, a gem-diolate transition state analogue, by X-ray crystallography, Biochemistry 34 14792-14800... 

H Kim, WN Lipscomb (1994) Structure and mechanism of bovine lens leucine aminopeptidase, Adv Enzymol Relat Areas Mol Biol 68 153-213... 

A Taylor, M Daims, J Lee, T Surgenor (1982) Identification and quantification of leucine aminopeptidase in aged normal and cataractous human lenses and ability of bovine lens LAP to cleave bovine crystallins, Curr Eye Res 2 47-56... 

Maren TH (1967) Carbonic anhydrase Chemistry, physiology, and inhibition. Physiol Rev 47 595-781 Philpot FJ, Philpot JSL (1936) A modified colorimetric estimation of carbonic anhydrase. Biochem J 30 2191-2193 Wistrand PJ, Knuuttila K-G (1980) Bovine lens carbonic anhydrases Purification and properties. Exp Eye Res 30 277-290... 

Dicarboxy-5- methoxycoumarin] (coumarin) Semi-synthetic AR (bovine lens) (> 10)... 

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