Bombyx mori, amino acid sequence pheromone biosynthesis activating

In moths, it was discovered in Helicoverpa zea that a peptide produced in the subesophageal ganglion portion of the brain complex regulates pheromone production in female moths (19). This factor has been purified and characterized in three species, Helicoverpa zea (20), Bombyx mori (21, 22), and Lymantria dispar (23). They are all a 33- or 34-amino acid peptide (named pheromone biosynthesis activating neuropeptide, PBAN) and have in common an amidated C-terminal 5-amino acid sequence (FXPRL-amide), which is the minimum peptide fragment required for pheromon-tropic activity. In the redbanded leafroller moth, it was shown that PBAN from the brain stimulates the release of a different peptide from the bursae copulatrix that is used to stimulate pheromone production in the pheromone gland found at the posterior tip of the abdomen (24). 

Kitamura A., Nagasawa H., Kataoka H., Inoue T., Matsumoto S., Ando T. and Suzuki A. (1989) Amino acid sequence of pheromone biosynthesis activating neuropeptide (PB AN) of the silkworm, Bombyx mori. Biochem. Biophys. Res. Commun. 163, 520-526. 

Amino acid sequence of pheromone-biosynthesis-activating neuropeptide (PB AN) of the silkworm, Bombyx mori. Biochem. Biophys. Res. Commun. 163, 520-526. 

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