Blobel

Chirico, W.J., Waters, M.G., Blobel, G. (1988). 70 kDa heat shock related proteins stimulate protein translocation into microsomes. Nature 332, 805-810. 

The signal hypothesis was proposed by Blobel and Sabatini pardy to explain the distinction between free and membrane-bound polyribosomes. They found that proteins synthesized on membrane-bound polyribosomes contained a peptide extension (signal peptide)... 

Garton KJ, Gough PJ, Blobel CP, et al. Tumor necrosis factor-alpha-converting enzyme (ADAM 17) mediates the cleavage and shedding of fractalkine (CX3CL1). J Biol Chem 2001 276 37993-38001. 

Blobel, G., and Dobberstein, B. (1975a). Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma. J. Cell Biol. 67, 835—851. 

Walter, P., and Blobel, G. (1981a). Translocation of proteins across the endoplasmic reticulum III. Signal recognition protein (SRP) causes signal sequence-dependent and site-specific arrest of chain elongation that is released by microsomal membranes. J. Cell Biol. 91, 557-561. 

Walter, P., and Blobel, G. (1983). Preparation of microsomal membranes for cotranslational protein translocation. Methods Enzymol. 96, 84—93. 

Denney, J.B., and Blobel, G. (1984) 1251-Labeled cross-linking reagent that is hydrophilic, photoactivat-able, and cleavable through an azo linkage. Proc. Natl. Acad. Sci. USA 81, 5286-5290. 

Kessler F, Blobel G, Patel A, Schnell DJ. Identification of the two GTP-binding proteins in the chloroplast import machinery. Science 1994 266 1035-1039. 

Aitchison, D, Blobel, G, Rout, MP. Kap 104p a karyopherin involved in the nuclear transport of messenger RNA-DNA binding proteins. Science 1996 274 ... 

Most of the proteins on which fragment folding studies have been carried out are extracellular. Of the nine discussed in this article, only tryptophan synthetase and /3-galactosidase are not secreted. Many secreted proteins are synthesized with 20 or so additional amino acid residues at the N-terminus of the peptide chain (Blobel... 

Valentrn-Weigand, P., Grulich-Henn, J., Chhatwal, G. S., Muller-Berghaus, G., Blobel, H., and Preissner, K. T. (1988). Mediation of adherence of streptococci to human endothelial cells by complement S protein (vitronectin). Infect. Ininiun. 56, 2851-2855. 

Johnson, E. S., Sghwienhorst, I., Dohmen, R. j., and Blobel, G. The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aoslp/Uba2p heterodimer, Embo J, 1997, 36, 5509-19. 

Blobel, G. Protein targeting (Nobel lecture). Chembiochem 2000, I, 86-102. 

Matunis, M. j., Coutavas, E., and Blobel, G., a novel ubiquitin-like modification modulates the partitioning of the Ran-GTPase-activating protein RanGAPl between the cytosol and the nuclear pore complex,/. Cell. Biol., 1996, 135, 1457. 

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