Bladder cancer genetic factors

It is also clear that apart from exposure to carcinogens, other factors such as the genetic predisposition of the organism exposed may also be important. Thus, patients with the genetic disease xeroderma pigmentosum are more susceptible to skin cancer. It has already been mentioned that the incidence of bladder cancer is significantly higher in those individuals who have the slow acetylator phenotype. 

Kaisary A, Smith P, Jacqz E, et al. Genetic predisposition to bladder cancer ability to hydroxylate debrisoquine and mephenytoin as risk factors. Cancer Res 1987 47 5488-5493. 

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