Bismoles

Bismuth Subsalicylate. (2-Hydroxybenzoato-0 )-oxobismuth [14882-18-9] (Pepto-Bismol) maybe made by the process described in Reference 10. Bismuth subsaHcylate has been shown to bind toxins produced by several bacterial strains. It may also act as a result of its saHcylate component on prostaglandin formation and have specific intestinal antisecretory activity. It has been found to be effective in the prevention and therapy of... 

Bismuth subsahcylate [14882-18-9] Pepto-Bismol, is a basic salt of varying composition, corresponding approximately to i9-H0CgH4C02(Bi0). Like a number of other insoluble bismuth preparations, it is not currentiy approved in the United States for the treatment of peptic ulcer disease but is under active investigation for this purpose (180). It does appear to be effective for the rehef of mild diarrhea and for the prevention of travelers diarrhea (181). The ready availabiUty of this dmg, however, may lead to its ovemse and result in toxic effects caused by both the saUcylate and bismuth components. It has been suggested that bismuth subsahcylate is somewhat effective in the symptomatic treatment of isosporiasis, a disease caused by the intracellular parasite Isospora belli (182). 

WEB The active ingredient in Pepto-Bismol (an over-the-counter remedy for upset stomach) is bismuth subsalicylate, C7H5Bi04. Analysis of a 1.500-g sample of Pepto-Bismol yields 346 mg of bismuth. What percent by mass is bismuth subsalicylate (Assume that there is no other bismuth-containing compound in Pepto-Bismol.)... 

The attempted exchange reaction between 27 and phenylbismuth diiodide gave only intractable products. Apparently the bismole 31 is unstable under these Lewis acidic conditions. However, iodination of 27 gave 30 which, on lithiation followed by reaction with phenylbismuth diiodide, afforded the desired l-phenyl-2,5-dimethylbismole (31)," which could be... 

The reaction of the crowded stibole 53 and bismole 54 with lithium followed by addition of lithium cyclopentadienide (Scheme 9) gives mixtures of the corresponding monostibaferrocene 69 and monobismaferro-cene 70, respectively, with ferrocene.25 The more volatile ferrocene is easily removed by sublimation. Rather small amounts of the crowded diheteroferrocenes 55 or 56 are formed in this reaction. 

Bi Bi(sugar) polymers Antiulcer antacid Pepto-Bismol Ranitidine Bismutrex De-Nol... 

Peptizers, in tire compounding, 21 810 Pepto-Bismol, 4 36 Peptone, killing rate of e. coli, 8 64It Peracetic acid, 21 46-47 disinfection via, 8 630 production from acetaldehyde, 1 102, 111 Peracids, 9 369-370, 370-371, 372 10 378, 380... 

Heterocycles with Arsenic, Antimony, and Bismuth. Arsoles, stilboles, and bismoles (Scheme 54) are five-membered heterocycles for which experimental data do not indicate aromatic properties, while semiempirical calculations (CNINDO or CNDO/ S) showed that the anions are aromatic. The chemistry and theoretical aspects in connection with their... 

Pepto-bismol 18 Percocet 79 Percodan 79 Pergolide 55 Peti-Colace 79 Perindoptil 55 Permax 55 Permethrin 55 Permitil 36... 

Bismuth is used to make the drugs such as Pepto-Bismol for upset stomachs and diarrhea and in medicine to treat intestinal infections. Bismuth is used in the cosmetics industry to provide the shine for lipsticks, eye shadow, and other products. 

Ostac Clodronate Pepto-Bismol Bismuth subsalicylate... 

Bismuth Subsalicylate (Pepto-Bismol) [Antidiarrheal/ Adsorbent] [OTC] Uses Indigestion, N, D combo for Rx of H. pylori Infxn Action Antisecretory anti-inflammatory E>o e Adults. 2 tabs or 30 mL PO PRN (max 8 doses/24 h) Feds. 3—6 y 1/3 tab or 5 mL PO PRN (max 8 doses/24 h) 5-9 y 2/3 tab or 10 mL PO PRN (max 8 doses/24 h) 9-72 y 1 tab or 15 mL PO PRN (max 8 doses/24 h) Caution [C, D (3rd tri), -] Avoid w/ renal failure Hx severe GI bleed Contra Influenza or chickenpox (T risk of Reye synd), ASA allergy (see Aspirin) Disp Chew tabs, caplets, Liq, susp SE May turn tongue stools black Interactions T Effects OF ASA, MTX, valproic acid effects OF tetracyclines i effects W/ corticosteroids, probenecid EMS Monitor for hypovolemia and electrolyte disturbances d/t D may darken tongue stool OD Similar to ASA OD V, tinnitus, metabolic acidosis activated charcoal may be effective... 

OTC Colo-Fresh, Devrom, Kaopectate, Pepto-Bismol, Pink Bismuth Combinations... 

Antidiarrheal agents Bismuth subsalicylate, 524 mg every 30-60 minutes as needed up to 8 doses daily Kaopectate, Pepto- Bismol, various generics Antidiarrheals should not be used if diarrhea is accompanied by fever > 101°F or if blood or mucus is present in stool. Bismuth salts can cause dark discoloration of the tongue and stools. Salicylates are absorbed and can cause tinnitus if coadministered with aspirin. 

Aspirin and other salicylates Antidiarrheals Pepto-Bismol (bismuth subsalicylate) Kaopectate (bismuth subsalicylate)... 

The first 1,3,2-diazastiboles and -bismoles were prepared from A, A -bisltrimethylsilyl)-1,4-diazabutadiene derivatives (derived from phenanthraquinone or benzil) and the appropriate MCI3 (M = Sb, Bi), as shown in Scheme 10.4 for the benzil derivative the crystalline compounds 47 and 48 are dimers. 

CaCOs Alka-2, Camalox, Chooz, Pepto-Bismol, Titracid. Titralac, Turns... 

Condensed Ring Systems containing an Arsole, Stibole or Bismole Ring 547... 

Five-membered Ring Systems containing Two Double Bonds 1.18.3,3.1 Arsoles, Stiboles, Bismoles... 

The only monobenzo derivatives known are the arsindoles, whereas dibenzo compounds exist for arsole, stibole and bismole. 

Aluminum Hydroxide Magnesium Trisilicate (Gaviscon) Aluminum Hydroxide (Amphojel, ALtemaGEL) Aluminum Hydroxide + Magnesium Carbonate (Gaviscon Extra Strength, Liquid) Antidiarrheals Bismuth Subcitrate/ Metronidazole/ Tetracycline (Pylera) Bismuth Subsalicylate (Pepto-Bismol) Diphenoxylate w/ Atropine (Lomotil, Lonox)... 

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