Bis- -acetic acid

Chemical Name 2,2 -[ ([4-[(Aminocarbonyl)amino] phenyl] arsinidene] bis(thio)] bis (acetic acid]... 

Bis(acetic acid)trifluoroborane, 4 144t Bisacetoacetarylide, pigment for plastics, 7 366t... 

The stoichiometric equivalents of halofluorides have been recently applied to transform alkylene dithioacetals into gcm-difluorides.70-71 Dithioacetals such as 1,3-dithiolanes and 1,3-dithianes arc readily obtained from the corresponding carbonyl compounds by the reaction with ethane-1,2-dithiol or propane-1,3-dithiol in the presence of the complexes boron trifluoride-bis(acetic acid) or boron trifluoride-diethyl ether. Using a two-step procedure, a range of aldehydes and ketones can be converted into gem-difluorides under mild conditions. 

C. mcso-5-Norbornen-2,3-ylene-endo-bis(acetic acid). 26... 

C. mg50-5-NORBORNEN-2,3-YLENE-e/2rfo-BIS(ACETIC ACID)... 

C. meSO-5-NORBORNEN-2,3-YLEME-enrfo-BIS(ACETIC acid)... 

C12H2oCr20i2, Tetra-M-acetato-dichromium - bis(acetic acid), 44B,... 

C12H20UO12/ Bis(acetic acid)tetraacetatodicopper(11), 45B, 1112 Cl2H21CI2O1oRes, Tris-Ai-i-butyrato-bis(chlororhenium(III)) per-rhenate, 40B, 1116... 

Ethylene oxide adds to the bis(2-hydtoxyethyl) teitiaiy amine in a random fashion where x y y = n y2. Ethoxylated amines, varying from strongly cationic to very weakly cationic in character, are available containing up to 50 mol of ethylene oxide/mol of amine. Ethyoxylated fatty amine quaternaries, cationic surfactants (both chloride from methyl chloride and acetate from acetic acid), ate also available. 

The principal coloring matter in turmeric and its oleoresin is curcumin [458-37-7] (l,6-heptadiene-3,5-dione, l,7-bis[4-hydroxy-3-methoxy-phenyl] (45), an orange-yeUow, crystalline powder, insoluble in water and ether but soluble in ethanol and glacial acetic acid. It has a reported melting point of 180-183°C. 

Early experiments with pyridine-2,3-dicarboxylic mono- and bis-phenylhydrazides were unsuccessful (32JIC145), but later these were cyclized in acetic acid (66CPBIOIO) to give only the 7-phenylpyrido[2,3-[Pg.242]

Bis(2,4,6-trinitrophenyl)methane when treated with NaAc in acetic acid produced (580) as a thermostable explosive (80MIP41600). The conversion of o-nitrotoluene into 2,1-benzisoxazole was effected by mercury(II) oxide catalysis. A mercury containing intermediate was isolated and was demonstrated to be converted into 2,1-benzisoxazole (67AHC(8)277). The treatment of o-nitrotoluene derivative (581) with sulfuric acid gave (582) in 35% yield (72MI41607). 

NKOH, EtOH, 20°, 5-10 min 80% yield. 5-2,2-Bis(carboethoxy)ethyl thioether, stable to acidic reagents such as trifluoroacetic acid and hydrogen bromide/acetic acid, has been used in a synthesis of glutathione. ... 

N-2-cyanoethylaniline has been prepared (accompanied by much of the N,N -bis-2-cyanoethyl compound) by heating aniline, acrylonitrile and acetic acid either in an autoclave, or at refluxing temperature for 10 hours in the presence of various inorganic catalysts. The substance has also been obtained, free of the N,N -bis-2-cyanoethyl compound, from aniline salts and /3-diethylaminopropionitrile. ... 

In a 1-1. three-necked round-bottomed flask equipped with an eflicient stirrer, a reflux condenser, and a thermometer (Note 1) are placed 500 ml. of glacial acetic acid (Note 2), 29.0 g. (0.19 mole) of -aminoacetanilide (Note 3), 40 g. (0.26 mole) of sodium perborate tetrahydrate, and 10 g. (0.16 mole) of boric acid. The mixture is heated with stirring to 50-60° and held at this temperature for 6 hours. Initially the solids dissolve but, after heating for approximately 40 minutes, the product begins to separate. At the end of the reaction period, the mixture is cooled to room temperature and the yellow product is collected on a Buchner funnel. It is washed with water until the washings are neutral to pH paper (Note 4) and then dried in an oven at 110°. The yield of 4,4 -bis(acetamido)a2obenzene, m.p. 288-293° (dec.), is 16.5 g. (57.7%). It is used as such for the hydrolysis step (Note 5). 

Ferrocene (46.4 g., 0.250 mole) (Note 1) is added to a well-stirred solution of 43.2 g. (0.422 mole) of bis(dimethylamino)-methane (Note 2) and 43.2 g. of phosphoric acid in 400 ml. of acetic acid in a 2-1. three-necked round-bottomed flask equipped with a condenser, a nitrogen inlet, and a mechanical stirrer (Note 3). The resulting suspension is heated on a steam bath under a slow stream of nitrogen (Note 4) for 5 hours (Note 5). The reaction mixture, a dark-amber solution, is allowed to cool to room temperature and is diluted with 550 ml. of water. The unreacted ferrocene is removed by extracting the solution with three 325-ml. jiortions of ether. The aqueous solution is then looled in ice water and made alkaline by the addition of 245 g. 

We have noted above that benzocrowns may be nitrated quite readily. This approach was used in the formation of a photoresponsive bis-crown (see Sect. 3.8) wherein the nitrobenzo crowns reductively dimerize to the corresponding azobenzene. Kikukawa, Nagira and Matsuda have utilized 4-nitrobenzo-15-crown-5 in a somewhat different way during the synthesis of 4 -vinylbenzo-l 5-crown-5Nitration is effected using nitric acid in a mbcture of chloroform and acetic acid. 

Just as selective oxidation can be carried out on these systems, reduction also occurs with considerable selectively. Hydrogenation of binaphthol (Pd catalyst) in glacial acetic acid at room temperature for seven days affords the octahydro (bis-tetrahydro) derivative in 92% yield with no apparent loss of optical activity when the reaction is conducted on optically pure material. The binaphthol may then be converted into the bis-binaphthyl crown in the usual fashion. 

Molybdenum hexafluoride, in the presence of boron trifluonde, reacts with acetic acid and haloacetic acids at 130-160 °C to give respectively, 1,1,1 tri fluoroethane and 1,1 1 trifluorohaloetlianes in 60-89% yields [2d0, 241] Prolonged treatment of pyridine mono and dicarboxylic acids with an excess of molybdenum hexafluoride at elevated temperatures provides the respective mono-and bis(trifluoromethyl)pyridines in good yields [241] (equation 127)... 

Tertiary Af-alkyl-Al,(V-bis(2-fluoro-2,2-dinitroethyl)atnines containing 77-methylene or A -methyl groups are oxidized by chromium trioxide in acetic acid to Af,Al-bis(2-fluoro-2,2-dimtroethyl)formamides [ 5] (equation 82)... 

To a solution of the ester amide (160 mg, 0.26 mmol) in methanol (3 mL) and THF (3 mL) was added a 1 M solution of NaOMe in methanol (5 mL). The mixture was stirred at rt for 1.5 d then neutralized with methanolic acetic acid and concentrated in vacuo. The crude material was partitioned between water and CH2CI2. The organic phase was dried over anhydrous magnesium sulfate, filtered, and concentrated in vacuo to afford the bis(ester) 73 as a colorless solid, mp 154.4-155.5 C, [a] -17° (c = 0.3, MeOH). 

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