Biosensing system

Operational schematic of discontinuous biosensing system (assay), 16 3-3 Key characteristics of sensor systems, 17... 

FIGURE 3-2 Operational schematic of discontinuous biosensing system (assay). 

K. Kamei, T. Haruyama, M. Mie, Y. Yanagida, M. Aizawa, and E. Kobatake, The construction of endothelial cellular biosensing system for the control of blood pressure drugs. Biosens. Bioelectron. 19, 1121-1124(2004). 

Current research studies involve numerous efforts in improving the analytical performance of the biosensing systems in order to be able to... 

Engineered variants of enzymes could be another approach in biosensor design for the discrimination and detection of various enzyme-inhibiting compounds when used in combination with chemometric data analysis using ANN. The crucial issues that should be addressed in the development of new analytical methods are the possibility of simultaneous and discriminative monitoring of several contaminants in a multi-component sample and the conversion of the biosensing systems to marketable devices suitable for large-scale environmental and food applications. 

M.D. Luque de Castro and M.C. Herrera, Enzyme inhibition-based biosensors and biosensing systems questionable analytical devices, Biosens. Bioelectron., 18 (2003) 279-294. 

A microdialysis probe could help to overcome some of these problems by acting as a protective interface between the bioreactor and the biosensing system, at the same time allowing on-line detection of the selected analyte. In fact, the microdialysis probe can be easily sterilized, thus avoiding problems of contamination. Membranes impermeable to bacteria would also act as a sterile barrier between the interior of the bioreactor and the analysis... 

Surface plasmon resonance biosensing system hESC-derived cardiomyocytes cTnT and FABP3 release in the medium... 

Shoji S (2000) Micromachining for biosensors and biosensing systems. In Yong VC, Ngo TT (eds) Biosensors and their applications. Kluwer Academic/Plenum Pub, New York, pp 225-241... 

The objective of this study is to provide an overview of the systems available for the bioassay of herbicide pollutants affecting directly photosynthetic activities. Since biological detection reflects the true physiological consequence of pollutants, such a system makes it possible to monitor even trace amounts of chemicals. It is foreseeable that advanced biosensing systems based on PSII may eventually substitute for the current cosdy chemical techniques. 

Various nanomaterials, including carbon nanotubes, nanoparticles, nanomagnetic beads, and nanocomposites, are being used to develop highly sensitive and robust biosensors and biosensing systems [1] with a special emphasis on the development of electrochemical-based (bio) sensors [2,3] due to their simplicity and cost efficiency. 

The first biosensor was based on an enzyme electrode and developed for glucose analysis in 1962 [16]. Then many researches have focused on biosensing systems. This is mostly due to the biosensor s high selectivity and sensitivity [17]. In 1975, Divis proposed microorganism electrode for determining the alcohol level in a solution [18]. Also, same year the first glucose biosensor was produced commercially by Yellow Springs Instruments. 

Davidsson R, Johansson B, Passoth V, Bengtsson M, Laurell T, Emneus J (2004) Microfluidic biosensing systems - Part 11. Monitoring the dynamic production of glucose and ethanol from mierochip-immobilised yeast cells using enzymatic chemiluminescent mu-biosensors. Lab Chip 4(5) 488-494... 

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