Bioresorbable polymers pharmaceutical fields

Bioresorbable polymer microparticles in the medical and pharmaceutical fields... 

In the field of bioresorbable polymers, dendrimers are usually not included. In contrast, polymerosomes, polymeric micelles, and polymeric NPs find a large number of applications as bioresorbable systems, mainly in dmg delivery. It is an extremely vast field of research that covers the development and use of innovative systems for the administration of pharmaceutically active ingredients. In this case there are numerous administration routes for dehvering the active ingredients loaded in these systems, such as oral, transmucosal, pulmonary, and intravenous. The preferable route is oral (noninvasive dehvery), although very often it is not feasible, as with anticancer compounds for which the intravenous route (invasive delivery) is preferred (Fig. 12.1) [1]. 

To satisfy the requirements of biocompalibility and biodegradability, the materials used in medical and pharmaceutical fields for intravenous injection are generally characterized by polymeric NPs based on polyesters, which are biocompatible and biodegradable. In this chapter, we cover the most common bioresorbable polymer materials that are synthesized. Then, we discuss the methods adopted for the synthesis of NPs made of bioresorbable polymers. Finally, we present the most common applications of bioresorbable polymer NPs in medical and pharmaceutical fields and the hurdles involved in their use. 

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