Bioresorbable polymers controlled release

Abstract The main families of synthetic bioresorbable polymers, which find wide medical application as temporary mechanical supports such as sutures, as tissue engineering scaffolds, and as mediators of release rate for the controlled release of drugs are outlined. The physical and chemical mechanisms by which they degrade are discussed and the factors that can affect their rates of degradation are examined. 

A second application is the controlled release of the polymer. Here, we report two different examples. The first example is a bioabsorbable suture. A suture is defined as bioabsorbable in solid polymeric materials or devices if it can dissolve in body fluids without any polymer chain cleavage or molecular mass decrease. Another example is a water-soluble implant that undergoes slow dissolution in body fluids. A bioabsorbable polymer also can be bioresorbable if the dispersed macromolecules are excreted [6]), or it is a MD belonging at least to class 11b [4] but usually to class 111 (release a drug with an ancillary function or it is completely resorbable) [5],... 

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