Fluorescent bioprobes

The novel /V-hcicrocyclic carbene (NHC) l,3-dicyclohexyl-l,3-diazepan-2-ylidene 80 and its 5,6-dioxolane derivative 81 were synthesised and their coordination chemistry with Rh(I), Ir(I), and Pt(0) explored. The coordinated carbene ligands display extremely large NCN bond angles in crystal structures <0704800>. The cyclic urea 82 was synthesised and fluorescent properties studied in a search for new DNA/RNA bioprobes <07JOC102>. 

A different type of ethanol bioprobe was designed on the basis of an NAD -dependent dehydrogenase reaction [81]. Alcohol dehydrogenase plus NAD was retained at the end of a fiber by a microporous PTFE membrane, and the rate of formation of fluorescent NADH... 

Coupling of commercially available streptavidin-coated QDs with a biotin-ended lactose glycopolymer took place in one hour at room temperature to produce fluorescent bioprobes. Likewise, biotinylated Le, or HTV-l envelope glycoprotein gpl20, were... 

Wu Y, Chu M, Shi B, Li Z (2011) A novel magneto-fluorescent nano-bioprobe for eaneer eell targeting, imaging and collection. Appl Biochem Biotechnol 163(7) 813-825... 

Jayasree A, Sasidharan S, Koyakutty M, Nair S, Menon D (2011) Mannosylated chitosan-zinc sulphide nanocrystals as fluorescent bioprobes for targeted cancer imaging. Carbohydr... 

Hayek A, Bolze F, Bourgogne C, Baldeck CL, Didier P, Amtz Y, Mely Y, Nicoud JF (2009) Boron containing two-photon absorbing chromophores. 2. Fine tuning of the one- and two-photon photophysical properties of pyrazabole-based fluorescent bioprobes. Inorg Chem 48 9112-9119... 

Deng, K Chen, j. and Tan, W. (2007) Rhodamine B isothiocyanate doped sflica-coated fluorescent nanopartides (RBITC-DSFNPs)-based bioprobes conjugated to Annexin V for apoptosis detection and imaging. Ncmomedicine, 3, 266-72. 

Zhang, J., Jia, X., Lv, X.-J., Deng, Y.-L., and Xie, H.-Y. Fluorescent quantum dot-labeled aptamer bioprobes specifically targeting mouse bver cancer cells. Talanta 81,505-509,2010. 

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