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Biophysical characterization electrophoresis

The application of high-performance capillary zone electrophoresis (HP-CZE) in its various selectivity modes has become a very valuable adjunct to HPLC for the analysis of peptides. For synthetic peptides, in particular, both HPLC and HP-CZE now form essential components of the analytical characterization of these molecules. Increasingly, zonal, micellar, or (biospecific) affinity-based HP-CZE procedures with open tubular capillary systems are adapted to allow resolution with extremely high separation efficiencies (e.g., >105 plates per meter) of synthetic or naturally occurring peptides as part of the determination of their structural, biophysical, or functional properties. Illustrative of these capabilities are the results shown in Figure 19 for the separation of several peptides with different charge and Stokes radius characteristics by HP-CZE. [Pg.609]


See other pages where Biophysical characterization electrophoresis is mentioned: [Pg.234]    [Pg.158]    [Pg.216]    [Pg.74]    [Pg.1712]    [Pg.2224]    [Pg.490]    [Pg.165]    [Pg.103]    [Pg.579]    [Pg.866]   
See also in sourсe #XX -- [ Pg.158 , Pg.159 , Pg.160 , Pg.161 , Pg.162 , Pg.163 , Pg.164 ]




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