Biomimetic nanocomposite hydrogels for cartilage regeneration

The George Washington University, Washington, DC, United States 

Advances in materials and scaffold design have also included biochemical cues that mimic those found within articular cartilage exhibiting improved cell adhesion, pro-hferation, directed differentiation, and phenotypic expression (Chen et al., 2011 Guo et al., 2010). Extended culture approaches, in which cartilage-like tissue is secreted by 

Image is adapted from Trruvannamalai-Annamalai, R., Araiant, D.R., Matthew, H.W., 2014. 

A glycosaminoglycan based, modular tissue scaffold system for rapid assembly of perfusable, high cell density, engineered tissues. PLoS One 9, e84287. 

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