Biological research function

Marches , V. T, 1984. Structure and function of die erydirocyte membrane skeleton. Progress in Clinical Biology Research 159 1 — 12. 

The use of biochips in basic biological research has provided information that was heretofore inaccessible. Protein chips, especially functional microarrays, are used to... 

Two ways, then, could make biological research in psychiatry more diagnostically meaningful precise definition of the syndromes to be studied and their systematic functional analysis. Methods to carry out such analyses in a... 

Figure 15.2 Target validation and functional analysis overview of the methods currently available to biological researchers. Modified from Blackstock (1999).

EMBL was founded with a four-fold mission to conduct basic research r) molecular biology, to provide essential services to scientists in its Member States, to provide high-level training to its staff, students, and visitors, and to develop new instrumentation for biological research. These core functions are combined with significant outreach activities m the areas of technology transfer, science and society and training for science teachers. 

Raamsdonk and colleagues set out to develop a metabolomics method that could be used to characterize proteins of unknown function in yeast [14]. Using an NMR approach they analyzed intracellular metabolites in mutants of Saccharomyces cerevisiae. The resulting NMR spectra were then analyzed by multivariate analysis, including principle component analysis (PCA) to identify differences in the spectra that can distinguish different mutants (Fig. 2). Two important results came out of these studies that would reveal the value of metabolomics in biological research. 

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