Biological properties, tars

Biological Properties of Tars Just as physical properties of tars can be related to their chemical composition, so can biological activities of the tars Biological activity can be categorized as either short-term, as in acute toxicity, or long-term, as in... 

B. ftfliovd and J. Kopecek, Biological properties of tar-getable poly- [N-(2-hydroxypropyl)methacrylamide]-antibody conjugates, /. Control. Release, 2, 289-310 (1985). 

Phenol is a product of the refining of oil and coal tar and is used industrially in the manufacture of pharmaceuticals, plastics, rubber, and plywood. It has antiseptic, germicidal, and anesthetic properties and may be used in disinfectants and preservatives. It is used in small amounts in many over-the-counter products with antiseptic properties. It is also a common reagent in nucleic acid/molecular biology research and is used to denature and remove protein from preparations of DNA and RNA. 

The high resolving power of capillary gas chromatography (GC) is required for the successful analysis of coal-derived materials, since these mixtures can contain hundreds of components with very similar chemical properties. Guillen et al. (1992) and Blanco et al. (1992) have demonstrated the full power of capillary GC using both mass spectrometry (MS) and flame ionization detection (FID) for analyzing coal tar. Specific applications for biological and environmental analyses are described below. 

Thiophene was found in tar, gas and industrial benzene obtained from coal in the nineteenth century. A large number of thiophene derivatives are described in the literature and their physical properties, nucleophilic substitution and biological activity are still of current interest [ ] As for polymers, thiophene was oxidized by such acidic materials as orthophosphoric acid or a synthetic silica-alumina catalyst to yield liquid oligomer which consisted of its trimer containing a small amount of its pentamer. A report on this was published as early as 1883 [2], However, modem studies on polythiophene, aiming at the preparation of electrically conductive polymers, started at the beginning of the 1980s [3-5]. 

In addition to being liuninescent molecttlar tags, several types of rare earth complexes exhibit elaborate molecular recognition properties for biological substrates. A new class of DNA tar-... 

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