Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Biological apatites, fluoride ions

The effect of fluoride on odontoblast seems to follow similar pathways however, fluoride does not seem to show any effect on the proliferation of ameloblast cells. In addition to direct biological effects, fluoride ions may also exhibit indirect effects related to the decrease in Calcium concentration they can involve, and the change in the surface properties of biological apatites. [Pg.319]

There are multiple applications of fluoridated bioceramics, essentially as bone and tooth substitutes (Table 1), involving bulk ceramics, glasses, composite materials and coatings for medical devices and surface treatments. In some cases, fluoride ions can leach out of the material inducing a direct biological effect in a soluble form. However, considering the affinity of fluoride ions for apatite... [Pg.281]

Fig. 8. Evolution of synthetic and biological apatites in the presence of fluoride ions. The increase of pH and/or phosphate concentration in solution favours the formation of fluoridated apatite, whereas the increase of fluoride and/or calcium concentration favours CaF2 formation. At physiologic pH and mineral ions concentrations (in all body fluids), the formation of fluoridated apatite is favoured. Fig. 8. Evolution of synthetic and biological apatites in the presence of fluoride ions. The increase of pH and/or phosphate concentration in solution favours the formation of fluoridated apatite, whereas the increase of fluoride and/or calcium concentration favours CaF2 formation. At physiologic pH and mineral ions concentrations (in all body fluids), the formation of fluoridated apatite is favoured.
The first and primary protective effect of fluoride is due to its strong, spontaneous reaction with metal ions. Biologically, the most important of these ions is the calcium ion, large amounts of which interact with phosphate to form bones and teeth. Studies show that fluoride reduces apatite solubility in acids by an isomorphic replacement of hydroxide ions with fluoride ions to form fluoro-hydroxyapatite and difluoro-apatite (Fig. 16.6a). [Pg.292]

Substitutions in the HA structure are possible. Substitutions for Ca, PO4, and OH groups result in changes in the lattice parameter as well as changes in some of the properties of the crystal, such as solubility. If the OH" groups in HA are replaced by F" the anions are closer to the neighboring Ca " ions. This substitution helps to further stabilize the structure and is proposed as one of the reasons that fluoridation helps reduce tooth decay as shown by the study of the incorporation of F into HA and its effect on solubility. Biological apatites, which are the mineral phases of bone, enamel, and dentin, are usually referred to as HA. Actually, they differ from pme HA in stoichiometry, composition, and crystallinity, as well as in other physical and mechanical properties, as shown in Table 35.7. Biological apatites are usually Ca deficient and are always carbonate substituted (COs) " for (P04). For... [Pg.642]

Human teeth are also composed primarily of biological apatite. The outer two layers of a human tooth consist of enamel on the outside and dentine underneath that. Dentine and bones are very similar in composition and mechanical properties, but enamel is almost pure hydroxyapatite, Ca5(P04)30H. Dental enamel is the hardest part of the human body. In addition, the hardness of dental enamel is enhanced by the presence of fluoride ions in place of the hydroxides. (Thus we see... [Pg.367]

Synthetic fluor-containing apatites are prepared and investigated for biomedical applications and serve also as models to understand the formation of biological fluorapatites and some of their properties. The synthesis of fluoridated apatites has been accomplished in various ways from simple ion exchange in solution to more elaborate techniques involving sol-gel routes or thermal processes. Two main classes of synthesis routes are presented in this chapter high-temperature routes and low-temperature solution routes. [Pg.306]


See other pages where Biological apatites, fluoride ions is mentioned: [Pg.280]    [Pg.280]    [Pg.281]    [Pg.283]    [Pg.284]    [Pg.316]    [Pg.321]    [Pg.322]    [Pg.491]    [Pg.132]    [Pg.127]    [Pg.445]    [Pg.430]    [Pg.302]    [Pg.300]    [Pg.149]   
See also in sourсe #XX -- [ Pg.316 , Pg.317 , Pg.318 ]




SEARCH



Apatit

Apatite

Fluorid-Ion

Fluoride ion

© 2024 chempedia.info