Biointeractive polymers

Greisler HP, Gosselin C, Ren D, Kang SS, Kim DU. Biointeractive polymers and tissue engineered blood vessels. Biomaterials 17 329-336,1996. 

FIGURE 5.18 Schematic representation of a ceU membrane decorated with glyco-polymers indicating their specific biointeractions. Source Voit and Appelhans [39a], figure 1. Reproduced with permission Irom John Wiley Sons. 

Due to this progress that has been made in the recent years and the high impact on biotechnology and biomedicine, this textbook will provide the basic synthetic tools available to tailor-make multifunctional polymers and to control their biointeractions and self-assembly, and on the other hand, it will highlight functional materials and system applications that are based on the availability of such complex and multifunctional macromolecules. 

Williams, D.E (1994) Molecular biointeractions of biomedical polymers with extracellular exudate and inflammatory cells and their effect on biocompatibility, in-vivo. Biomaterials. 15, 779-785. 

Affinity chromatography is a special LC method that uses specific biointeractions. There is no single gel that is widely used. However, a substrate gel to fix affinity ligand is commercially available. Representative examples include polysaccharide or organic polymer gels that contain primary amine, carboxylic acid and epoxy groups [10]. 

---