Bioinformatics data management

Bioinformatics tools involving computer-based statistical analyses are essential for data management and analysis. When a complex biological sample containing thousands of different proteins is analyzed by multifaceted approaches, such as multidimensional protein identification technology, the identification of the proteins in the mixture is extremely complicated. Even multiple peptide identification methods, such as using both MS and... 

The European Bioinformatics Institute (EBI). This site is located at Hinxton Hall, Cambridge, UK. The home of the EMBL Nucleotide Sequence Database data management tools [including publicly accessible version of SRS—the Sequence Retrieval System (7)] protein family databases microarray tools etc. An extensive repository of resources for bioinformatics. 

Bernauer, S., D. Croft, P Gardina, E. Minch, M. de Rinaldis, and I. Vatcheva 2004. Case study Data management strategies in an integrated pathway tool. Appl Bioinformatics 3 63-75. 

The construction of a fully automated laboratory where all manual steps - from chemical synthesis to product characterization - are managed by robots is no longer a futuristic dream. Currently, about 20 companies are specialized in the design of chemistry robots of different sizes and levels of automation [15,16 Chapt. 19]. The robotized laboratory for chemical synthesis has to be connected with databases for building blocks, for reaction information, and for library information.The tools for data analysis should be accessible to the operator to design libraries and lead optimization in cooperation with specialists for screening, bioinformatics, database management, computational and medicinal chemistry, and for compound characterization. 

The most prominent ways to manage and exchange bioinformatics data are as follows ... 

Robert, V. (2003) Data management and bioinformatics. In Yeasts and Food (eds T. Boekhout and V. Robert), Behr s Verlag, Hamburg, Germany, pp. 139-170. 

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