Bioheat transfer modeling

Pennes Bioheat Transfer Model. It is known that one of the primary functions of blood flow in a biological system is its ability to heat or cool the tissue, depending on the relative local tissue temperature. The existence of a temperature difference between the blood and tissue is taken as evidence of its function to remove or release heat. On the basis of this speculation, Pennes [Pennes, 1948] proposed his famous bioheat transfer model, which is called Pennes bioheat equation. Pennes suggested that the effect of blood flow in the tissue be modeled as as heat source or sink term added to the traditional heat conduction equation. The Pennes bioheat equation is given by... 

Zhu et al. [61] developed a cylindrical geometry testing apparatus which incorporates a novel bioheat transfer model to test flame resistant fabric used in fire fighters protective wear. In the geometry test, heat flows from the radiant source, to the surface of the fabric and then through the fabric. It then flows through in air gap to the surface of a skin simulant. The rise in temperature on the surface of the skin simulant is used to determine the heat flux. This data is then applied to the thermal wave model of bioheat transfer, introduced by Liu et al. [62], the general form of which is ... 

In this chapter we start with fundamental aspects of local blood tissue thermal interaction. Discussions on how the blood effect is modeled then follow. Different approaches to theoretically modeling the blood flow in the tissue are shown. In particular the assumptions and validity of several widely used continuum bioheat transfer equations are evaluated. Different techniques to measure temperature, thermophysical properties, and blood flow are then described. The final part of the chapter focuses on one of the medical applications of heat transfer, hyperthermia treatment for tumors. 

Provides more detailed examples in bioheat transfer and pharmacokinetics which may be useful in modeling heat and mass transfer in the brain parenchyma. 

Chamy, C.K., Mathematical models of bioheat transfer, in Bioengineering Heat Transfer Advances in Heat Transfer,Y.. Cho, Ed., 1992, Academic Press Boston, pp. 19-155. 

Baish, J.W., J.K. Miller, and M.J. Zivitz, Heat transfer in the vicinity of the junction of two blood vessels, in Advances in Bioheat and Mass Transfer Microscale Analysis of Thermal Injury Processes, Instrumentation, Modeling and Clinical Applications, R.B. Roemer, Ed., 1993, ASME New York, pp. 95-100. 

Assuming that skin tissue above an isothermal core is maintained at a constant body temperature, Pennes [54] proposed one of the first bioheat models to deseribe heat transfer in... 

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