Bioenergetics Membrane Transport

Robinson, ID. 1997. Moving Questions A History of Membrane Transport and Bioenergetics. Oxford University Press, New York. 

Ion-binding studies with biological molecules can be important in elucidating fundamental biochemical reaction systems in relation to bioenergetics, enzyme activation and membrane transport [182]. For example, the adenosine triphosphate (ATP)—adenosine diphosphate (ADP) cycle is one of the processes of primary importance to cellular energy systems and association constants determined [427—430] for metal—ATP and metal—ADP complexes are therefore of considerable interest Table 2.5). The constants may be obtained from measure-... 

Absorption Bioenergetics Ion Transport Across Biological Membranes Pharmaceuticals, Controlled Release oe... 

Kostyuk, P. G. Electrical events during active transport of ions through biological membranes, in Topic in Bioelectrochemistry and Bioenergetics, Vol. 2, (ed.) Milazzo, G., New York, Wiley 1978... 

Ernster, L. (ed.), Bioenergetics. Amsterdam Elsevier, 1984. A collection of reviews covering electron transport, the ATP-synthase, translocation of ions across the mitochondrial inner membrane, thermogenesis in brown fat, and other topics in bioenergetics. 

Membrane Assembly in Living Systems Bioenergetics and Oxidative Metabolism Lipid Rafts Ion Transport... 

My major scientific personal interest lies in understanding the mechanism of proton pumping by cytochrome c oxidase. We are interested in more membrane proteins, and turn from bioenergetics more towards receptors and transporters. 

The issue of whether or not lipids are protective becomes more complicated when one considers that toxicants can affect lipid metabolism. Capuzzo and Leavitt16 observed increases in non-polar/polar lipid ratios in the tissues of PAH/PCB contaminated mussels and speculated that these contaminants mediate a decrease in the conversion of storage lipids to membrane lipids. Membrane-mediated solute transport, cell signaling, and bioenergetics are all significantly affected by membrane lipid composition53, and alterations in the proportion of membrane lipids in a tissue could seriously affect membrane integrity and function. 

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