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Biodegradable polymeric nanoparticles

Preparation of Biodegradable Polymeric Nanoparticles 2.1 PLGA Nanoparticles... [Pg.36]

Soppimath KS, Aminabhavi TM, Kulkami AR et al (2001) Biodegradable polymeric nanoparticles as dmg delivery devices. J Control Release 70 1-20... [Pg.56]

Kumari A, Yadav SK, Yadav SC (2009) Biodegradable polymeric nanoparticles based drug delivery systems. Colloids Surf B 75 1-18... [Pg.57]

Lee PW, Peng SF, Su CJ et al (2008) The use of biodegradable polymeric nanoparticles in combination with a low-pressure gene gun for transdermal DNA delivery. Biomaterials 29 742-751... [Pg.62]

Guzman LA, Labhasetwar V, et al.. Local intraluminal infusion of biodegradable polymeric nanoparticles. Circulation 1996 94 1441-1448. [Pg.489]

Pridgen EM, Langer R, Farokhzad OC (2007) Biodegradable, polymeric nanoparticle delivery systems for cancer therapy. Nanomedicine 2 669-680 Rzaev ZMO, Dincer S, Piskin E (2007) Functional copolymers of N-isopropylacrylamide for bioengineering applications. Prog Polym Sci 32 534—595 Schild HG (1992) Poly (N-Isopropylacrylamide) - experiment, theory and application. Prog Polym Sci 17 163-249... [Pg.265]

Gomez-Graete C, Tsapis N, Besnard M, Bochot A, Fattal E et al. (2007) Encapsulation of dexamethasone into biodegradable polymeric nanoparticles. Lnt. J. Pharm. 331 153-159. [Pg.85]

FIGURE 53.11 Cartoon diagram showing biodegradable polymeric nanoparticle drug delivery system. The nanoparticle drug delivery system has a dimension of about 50-100 nm. [Pg.1266]

Soppimath, K.S., Aminabhavi, T.M., Kulkami, A.R., Rudzinski, W.E. Biodegradable polymeric nanoparticles as drug delivery devices. J. Contr. Release, 70, 1, 2001. [Pg.1376]

Chorny M, Polyak B, Alferiev IS, Walsh K, Friedman G, Levy RJ. Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles. FASEB J, 2007, 21(10), 2510-19. [Pg.255]

Table 1 Various biodegradable polymeric nanoparticles used for delivery of different drugs... Table 1 Various biodegradable polymeric nanoparticles used for delivery of different drugs...
Shah LK, Amiji MM (2006) Intracellular delivery of saquinavir in biodegradable polymeric nanoparticles for HIV/AIDS. Pharm Res 23 2638-2645... [Pg.199]

Biodegradable polymeric nanoparticles have been prepared and used to enhance the stability of proteins and peptides, control their release and pharmacokinetic parameters, furthermore, to improve their bioavailability. For delivery purposes, the polymeric material needs to meet physicochemical and biological requirements, of which, biocompatibility, safety, and biodegradability into non-toxic metabolites are of cmcial importance. The polymers can be easily functionalised towards off opsoni-sation. They are also known to show reduced toxicity in the peripheral healthy tissues. The selection of polymers depends on the method of administration, the bioactive molecules to be loaded, the desired release profile, the intention to target specific tissues, the desired rate of particle degradation, and the biocompatibility. Table 11.3 outlines some of the natural and synthetic polymers currently used in the fabrication of nanoparticles. [Pg.332]

Couweur, R, Grislain, L., Lenaerts, V., Brassenr, R, Guiot, R. and Biernacki, A. (1986) Biodegradable polymeric nanoparticles as drug carrier for antitumor agents. In Polymeric nanoparticles and microspheres (Guiot R. and Couweiir R, Eds.). CRCPress, Boca Raton, Florida, pp. 27—93. [Pg.206]

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