Biocompatible transition metals

The author s own interest in this area includes new functional polymers for solid phase synthesis [11-13], polymers with molecularly imprinted substrate selectivity [14], polymer-supported transition metal catalysts [15], novel polymers of potential interest for electrocatalysis [16], targeting of colloidal drug carriers [17, 18], molecular composites [19], and biocompatible surfaces [20]. These studies have led to, among other things, a uniquely versatile method of polymer synthesis based on the chemistry of activated acrylates, i.e. polymer synthesis via activated esters. Various aspects of polymers and copolymers of activated (meth)acrylates have also been investigated in this and several other laboratories. 

Recently, inexpensive and biocompatible iron complexes have attracted much attention as a transition-metal catalyst in organic synthesis. Iron porphyrins are easy to handle and now commercially available. Liu and Che reported that [Fe (F2o-tpp)Cl] (F2o-tpp = mejo-tetrakis(pentalluoro-phenyl)porphyrinato dianion) 6 is a highly reactive catalyst for aziridination of various alkenes with sulfonyl and aryl azides (Scheme 2.11) [16, 17]. In particular, aliphatic alkenes, which have lower reactivity than styrenes for aziridination, could also be applied in this reaction system. 

Phosphate glasses These have glass transition temperatures typically < 1000°C and thermal expansion coefficients which make them suitable for applications such as glass-to-metal seals and biocompatible materials. The Na MAS NMR spectra reported... 

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