Biochemical differentiation

NGF not only acts in a permissive fashion to facilitate the morphological and biochemical differentiation of the neurons and process outgrowth but is also instructive and plays a role in specifying the phenotype of the neuron [9]. 

Butyrate appears to have its most profound effects on neoplastic cells such as HeLa in addition to morphological and biochemical differentiation, the fatty acid inhibits cell growth (2). Previous studies have established a correlation between decreased ganglioside synthesis and malignant transformation (43-46). Transformed baby hamster kidney and newborn rat kidney cells exhibited a loss of GM3 and sialyl transferase activity (43,44). 

The process of biochemical differentiation is not an unre-solvable succession of predestined events. In rat liver several... 

Other examinations focused on the biochemical differentiation of ascites, such as determining cholinesterase (62) and interleukin-6 (18) as sensitive parameters for bacterial infection as well as evaluating the receptors (p55 and p75) for the tumour necrosis factor. (19) An ascites/serum quotient for ai-foetoprotein of > 1 suggests hepatocellular carcinoma an amylase quotient of > 1 is found in pancreatitis. 

Hindmarsh JT, Oliver as L, Greenway DC. Biochemical differentiation of the porphyrias. Clin Biochem 1999 32 609-19. 

Nelson, R. B. and Siman, R., Thrombin and its inhibitors regulate morphological and biochemical differentiation of astrocytes in vitro, Dev. Brain Res., 54, 359, 1990. 

Nevertheless, neither the original Oparin theory nor its more recent variants are especially satisfying accounts of the origins of life. Major deficiencies at present include the inability of this theory to account for the currently accepted phylogenetic and biochemical differentiation of Archaea, Bacteria and Eucarya inability to account for the presumed thermophilic characteristics of the earliest common ancestor of these groups and inability to account for the origin of chirality. See also Box 5 for phylogenetic relationships. 

Moreover, in the striatum, NT-4/5 not only promoted morphological and biochemical differentiation of GABAergic neurons, but also their survival, both in organotypic slice cultures (Ardlet et al., 1994), and in cultured dissociated neurons (Widmer and Hefti, 1994a Ventimiglia et al.,... 

Paoletti, C., Pushparaj, B., Florenzano, G., Capella, P. and Lercker, G., 1976. Unsaponifia-ble matter of green and blue-green algal lipids as a factor of biochemical differentiation of their biomasses. I. Total unsaponifiable and hydrocarbon fraction. Lipids, 11 ... 

Three major cell models obtained from human colon cancers have been used HT-29, and T84, and Caco-2. HT-29 is a cell line capable of secreting mucin it has been used to study the effect of mucin on drug absorption. The T84 cell line does not express biochemical differentiation markers and is not particularly useful for studying drug transport. However, the T84 ceU line does express P-glycoprotein and can be used to study the role of this efflux pump. ... 

Jones, C.L., Lonergan, GT. and Mainwaring, D.E. (1995). Acid-phosphatase positional correlations in solid-surface fungal cultivation a fractal interpretation of biochemical differentiation. Biochem. Biophys. Res. Commun., 20S, 1159-1165. 

M. Sensenbrenner, G. Labourdette, J.P. Delaunoy, B. Pettmann, G. Devilliers, G. Moonen and E. Bock, Morphological and biochemical differentiation of glial cells in primary culture, in Tissue Culture in Neurobiology , E. Giacobini, A. Vernadakis and A. Shahar, eds.. Raven Press, New York, pp. 385-395 (1980). 

The attachment of the inner cell mass to the polar trophoblast has previously identified the dorsal aspect of the embryo. So, the definition of the anterior-posterior axis by the appearance of the prochordal plate and the primitive streak actually constrains the whole system of three axes. It must be remembered that the cells in question began their various biochemical differentiations before those differentiations became microscopically visible in spatial coordinates. 

Nadal-Ginard B (1978) Commitment, fusion and biochemical differentiation of a myogenic cell line in the absence of DNA synthesis. Cell 15 855-864... 

Qinical studies in psychiatry are often hampered, too, by different diagnostic criteria. Efforts in biochemical differentiation [32] between NA- and 5-HT metabolism in depressive patients are under way [33], but the value of this differentiation has still to be proved. 

The argentaf cells of the intestine are differentiated in that they can synthesize 5-hydroxytryptamine, probably via 5-hydroxytryptophane. Another biochemical differentiation of nerve cells is observ in the dendritic melanocytes which, in the skin and the eye, are spedalized for the... 

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