BioByte database

Leo, A. J. The MedChem Database, BioByte Corp. and Pomona College, Daylight Chemical Information Systems, Mission Viejo, CA, 2003. 

Physicochemical Parameter Database, Medicinal Chemisry Project, Pomona College, Claremont, CA, USA (www.biobyte. com/bb/pr od/cqsar. html). 

Hansch, C., Hoekman, D., Leo, A., Weininger, D., Selassie, C.D. C-QSAR Database. Available from the BioByte Corporation, Claremont, CA, 2004, http //WWW. biobyte.com /... 

Medchem Database, Database maintained and published by BioByte Corp and Pomona College in cooperation with Daylight Inc., Copyright 1982-2000 BioByte Corp. and Pomona College, see http //www.biobyte.com. 

II. Product Summaries BioByte provides a variety of software solutions to the drug discovery scientist that range from a chemically-oriented database system to a unified driver for ClogP/CMRprograms. 

BioByte product offerings are diverse, easy to learn, yet powerful software packages for researchers, academics, and students. BioLoom, their next generation ClogP package, calculates hydrophobic and molecular refractivity parameters, but now is linked to their database which includes over 60,000 measured log P values, as well as 14,000 pKa s. A demo version is available for download. 

The MedChem database [64] contains the largest publicly available collection of more than 60,000 measurements of log P and log P> values, and it is available as a commercial product from BioByte Inc. (http //www.biobyte.com). This database provided experimental support for the development of the CLOGP program [65,66]. The PHYSPROP database [14] of Syracuse Research Inc. provides experimental logP values for 13,058 compounds. This database is publicly available at http //esc.syrres.com/interkow/KowwinData.htm. 

Of the numerous applications of Free-Wilson and Hansch analyses (the BioByte QSAR Database [76] contains about 9400 data sets on biological applications and another 9000 physicochemical relationships, July 2003) [60,66-68], only a few shall be discussed here to illustrate the most important features and problems. 

Hansch C, Hoekman D, Leo A, Weininger D, Selassie CD, C-QSAR database. Available from the BioByte Corporation, 201 West 4th St. Suite 204, Claremont, CA 91711. 

MedChem/BioByte QSAR Database Microsoft Corp. Molecular biology sequence database Molecular graphics programs at the Lawrence Livermore National Laboratory Molecular Model Types and Rendering Techniques Molecular Simulations Inc. 

C. Hansch, D. Hoekman, and A. Leo, Medchem/Biobyte QSAR Database (1996). Available from Biobyte Corp., 201 W. Fourth St., Suite 204, Claremont, CA 91711. World Wide Web address (URL) http //fox.pomona.claremont.edu/chem/qsar-db. 

Syracuse Research BioByte QSAR Database, MedChem Projea log P... 

This server is maintained by the Medicinal Chemistry Project as a service to the chemistry community and by Biobyte Corp. to provide information about its products. It includes MedChem Names Database-over 30000 compounds QSAR Database-6000 data sets physical and biological systems. URL http //medchem.claremont.edu/... 

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