Separation bioamines

As described above, the alkaloid histamine originates from histidine. Histamine also exists as a common alkaloid in the body and is, like dopamine (Section 1.2) and serotonin (Section 2.1), called a bioamine. In some instances this alkaloid is discussed separately from the main alkaloids as one of the bioamines. 

Liquid chromatographic separation techniques are useful for the simultaneous determination of various amino acids and bioamines. 

Concerning real-world samples, uncountable numbers of interfering substances, including peptides and other amino compounds, are present in the complicated biological matrices, such as tissues and physiological fluids. Therefore, selective liquid-phase separation techniques in combination with sensitive detection systems are indispensable approaches. The development of the novel reagents as well as novel separation techniques have definitely contributed (and will also continue to contribute) to expanding the frontiers of amino acid and bioamine research. 

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