Bioactive hydrogels

Lee SH, Moon JJ, West JL (2008) Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration. Biomaterials 29(20) 2962-2968... 

Ferreira, L. S., Gerecht, S., Fuller, J., Shieh, H. R, Vunjak-Novakovic, G., and Langer, R. Bioactive hydrogel scaffolds for controllable vascular differentiation of human embryonic stem cells. Biomaterials, 28, 2706-2717 (2007). 

Martin L, Alonso M, Moller M, Rodriguez-Cabello JC, Mela P (2009) 3D microstructuring of smart bioactive hydrogels based on recombinant elastin-like polymers. Soft Matter... 

Yamaguchi, N. and Kiick, K.L., Polysaccharide-poly(ethylene glycol) star copolymers as scaffolds for the production of bioactive hydrogels. Biomacromolecules 6,1921-30,2005. 

Miller, J. S., C. J. Shen, W. R. Legant et al. 2010. Bioactive hydrogels made from step-growth derived PEG-peptide macromers. Biomaterials. 31 3736-43. 

Seliktar, D., Zisch, A. H., Lutolf, M. P, Wrana, J. L., and Hubbell, J. A. 2004. MMP-2 sensitive, VEGF-bearing bioactive hydrogels for promotion of vascular healing. J Biomed Mater Res A, 68, 704-16. 

Taite, L.J., Rowland, M.L., Ruffino, K.A., et al. Bioactive hydrogel substrates probing leukocyte receptor-ligand interactions in parallel plate flow chamber studies. Aim. Biomed. Eng. 34, 1705-1711 (2006). doi 10.1007/sl0439-006-9173-x... 

The combination of the characteristics of synthetic and natural polymers to make hybrid hydrogels has become a direct approach to create bioactive hydrogel expands the design and application of hydrogels. 

Under mild conditions, leucine zipper domains form non-covalent cross-links between protein monomers, resulting in a macromolecular bioactive hydrogel... 

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