Biliary hamartoma

Bile-duct papillomatosis Biliary hamartoma Caroli s disease/syndrome Intrahepatic bile-duct adenoma Intrahepatic bile-duct cystadenoma... 

Orii, T., Ohkohchi, N., Sasaki, K., Satomi, S., Watanabe, M., Moriya, T. Cholangiocarcinoma arising from preexisting biliary hamartoma of hver. - Report of a case. Hepato-Gastroenterol. 2003 50 333-336... 

These lesions include simple (bile duct) cyst, autosomal dominant polycystic liver disease, biliary hamartoma, Caroli s disease, pyogenic and amoebic abscesses, intrahepatic hydatid cyst, biliary cystadenoma and cystadenocarcinoma, cystic subtypes of primary liver neoplasms, cystic metastases, and intrahepatic hematoma and biioma. 

Sonographic findings in biliary hamartomas have been described as either hypoechoic or anechoic small... 

Bile-duct adenomas are rare. Usually, they are solitary and < 2 cm in size. This type of adenoma is more often detected in men than in women (3 1) and it occurs in patients mainly over the age of 50. It is nearly always localized beneath the liver capsule. This adenoma has the form of a firm, whitish node and consists of bile-duct proliferations. It contains biliary acini and tubules which are lined with a layer of cuboid epithelium within loose fibrous, partially hyaline stroma. There is evidence of mononuclear inflammatory cells and, occasionally, lymph follicles. It is discussed that such biliary adenomas are peribiliary gland hamartomas. (162) There are no clinical or biochemical abnormalities, nor is there any tendency towards malignant degeneration. (161,163)... 

Benign biliary microhamartomas (= Meyenburg s complex) were described by H. von Meyenburg in 1918. They consist of small cysts developing from dilatations of the small (interlobular) bile ducts and are surrounded by fibrous stroma. The cysts are remnants of ductal plate malformations. Occasionally, typical ductal plates can also be detected. The hamartomas can reach a diameter of up to 0.5 (-1.0) cm. (s. fig. 32.18) Macroscopically,... 

Benign biliary ductular proliferations are seen in a variety of conditions associated with hepatic injury and subsequent metaplastic changes. Bile duct hamartomas (von Meyenburg complexes) are small collections of bile ductules displaying dilated ductules with contour irregularities, single layer of bland, cuboidal epithelium, and intraluminal bile. 

Gadolinium chelates some authors observed homogeneous enhancement of these lesions, some others a thin rim enhancement, whereas others did not find any enhancement (Mortel and Ros 2001 Maher et al. 1999 Martinoli et al. 1992 Murphy et al. 1989 Slone et al. 1993 Wohlgemuth et al. 1998). At MR cholangiography, bile duct hamartomas appear as multiple tiny cystic lesions that do not communicate with the biliary tree, helping in the differential diagnosis with Caroli s disease (Fig. 7.6b-d) (Luo et al. 1998). 

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