Bile leakage

Scintigraphic assessment of liver transplants is helpful (e.g. perfusion, rejection, bile-duct obstruction or bile leakage). (28)... 

Hayashibe, A., Sakamoto, K., Shinbo, M., Makimoto, S., Nakamoto, T New method for prevention of bile leakage after hepatic resection. J. Surg. Oncol. 94(1), 57-60 (2006)... 

Complications of percutaneous treatment include cholangitis (5%-6.5%), haemorrhage (2%), bile leakage (2%), abscess and catheter dislodgement (Cowling and Adam 2001 Rieber and Brambs... 

Vagus shock might also be caused by postbioptic biliary leakage with acute irritation of the serosa. H. Thaler observed this event 19 times in 7,500 biopsies we have witnessed it just once with 4,124 biopsied patients. This would suggest that bile-related acute irritation of the serosa is only in rare cases likely to be the cause of a peritoneal shock. 

Schlaeger R, Hairs P, Kattermann R. Studies on the mechanism of the increase in serum alkaline phosphatase activity in cholestasis Significance of the hepatic bile acid concentration for the leakage of alkaline phosphatase from rat liver, En2yme 1982 28 3-13. 

Bile contains a large number of diverse proteins, some resulting from leakage of hepatocellular protein and others derived from plasma (A9, R6). In certain cases, the liver may secrete specific proteins into bile to bind and thus prevent the reabsorption of potential toxins and thus facilitate fecal excretion of these substances (S3). As an example, copper is excreted principally by the biliary route, bound to a carrier protein that prevents intestinal absorption of the biliary copper (G6). The GST can bind a wide range of substances and we have studied the GST content of human bile using material obtained from intact gallbladders following removal at cholecystectomy. 

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