Beta-thromboglobulin

Nakamura, T., Ebihara, I., Shoji, H., Ushiyama, C., Suzuki, S., Koide, H. Treatment with polymyxin B-immobilized fiber reduces platelet activation in septic shock patients decrease in plasma levels of soluble P-selectin, platelet factor 4 and beta-thromboglobulin. Inflamm Res 48 (1999) 171-175. 

When 50 bipolar lithium patients were compared with 30 healthy controls, platelet counts were similar, but the lithium group had higher concentrations of plasma beta-thromboglobulin and platelet factor 4, suggesting lithium-induced platelet activation (338). 

Hemostasis can be impaired by both surgery and general anesthetics (45). Fentanyl, halothane, and enflurane enhance fibrinoljdic activity significantly (46). In addition, there was a raised plasma beta-thromboglobulin concentration (a good indicator of platelet activation) in 61 patients after the use of nitrous oxide, oxygen, and halothane compared with controls (47). 

Both platelet factor 4 (PF4) and beta thromboglobulin (BTG) are secreted when platelets aggregate. PF4 has a short... 

Connective tissue activating protein-III (CTAP-III) Beta-thromboglobulin (P-TG)... 

Holt, J. C., Rabellino, E. M., Gewirtz, A. M., Gunkel, L. M., Rucinski, B., and Niewiarowski, S. (1988). Occurrence of platelet basic protein, a precursor of low affinity platelet factor 4 and beta-thromboglobulin, in human platelets and megakaryocytes. Exp. Hematol. 16, 302-306. 

Majumdar, S., Gonder, D., Koutsis, B., and Poncz, M. (1991). Characterization of the human beta-thromboglobulin gene Comparison with the gene for platelet factor 4. J. Biol Chem. 266, 5785-5789. 

Richmond, A., Balentien, E., Thomas, H. G., Flaggs, G., Barton, D. E., Spiess, J., Bordoni, R., Francke, U., and Derynck, R. (1988). Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thromboglobulin. EMBO J. 7, 2025-2033. 

Walz, A., and Baggiolini, M. (1989). A novel cleavage product of beta-thromboglobulin formed in cultures of stimulated mononuclear cells activates human neutrophils. Biochem. Biophys. Res. Common. 159, 969 975. 

Laske, C., Stransky, E., Leyhe, T., Eschweiler, G.W., Schott, K., Langer, H., and Gawaz, M. 2006. Decreased brain-derived neurotrophic factor (BDNF)- and beta-thromboglobulin (beta-TG)-blood levels in Alzheimer s disease. Thrombosis and haemostasis, 96(1), 102-3. 

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