Beta-blockers in heart failure

Abraham WT, Iyengar S. Practical considerations for switching beta-blockers in heart failure patients. Rev Cardiovasc Med. 2004 5(suppl 1) S36-S44. [Pg.285]

Bauman JL, Talbert RL. Pharmacodynamics of beta-blockers in heart failure lessons from the carvedilol or metoprolol European trial. J Cardiovasc Pharmacol Ther. 2004 9 117-128. [Pg.285]

Fonarow GC. When to initiate beta-blockers in heart failure is it ever too early Curr Heart Fail Rep. 2005 2 94-99. [Pg.285]

Metra M, Cas LD, di Lenarda A, Poole-Wilson P. Beta-blockers in heart failure are pharmacological differences clinically important Heart Fail Rev. 2004 9 123-130. [Pg.345]

What is the role of beta-blockers in heart failure Summarise the clinical trial evidence to date. [Pg.28]

High-dose aspirin for carotid endarterectomy Beta-blockers in heart failure... [Pg.224]

Barnett DB. Beta-blockers in heart failure a therapeutic paradox. Lancet 1994 343(8897) 557-8. [Pg.469]

Bristow MR. Mechanistic and clinical rationales for using beta-blockers in heart failure. J Card Fail 2000 6 8-14. [Pg.259]

McAreavey D, Exner DV, Curtin EL, et al Beta-blockers in heart failure Recently completed and ongo-... [Pg.148]

Mangoni AA, Jackson SH. The implications of a growing evidence base for drug use in elderly patients. Part 3. Beta-adrenoceptor blockers in heart failure and throm-bolytics in acute myocardial infarction. Br J Chn Pharmacol 2006 61(5) 513-20. [Pg.223]

Sharpe N. Benefit of beta-blockers for heart failure proven in 1999. Lancet 1999 353(9169) 1988-9. [Pg.470]

In patients with chronic heart failure, the use of digoxin and beta blockers is typically sufficient to control heart rates, and the combination of digoxin with carvedilol has been shown to provide better overall rate control than either of them used alone in heart failure patients [42]. However, if the patient is either intolerant of beta blockers or they fail to... [Pg.53]

Brophy JM, Joseph L, Rouleau JL. Beta-blockers in congestive heart failure a Bayesian meta-analysis. Ann Intern Med 2001 134(7) 550-60. [Pg.597]

BETA BLOCKERS THAT HAVE REDUCED MORTALITY IN HEART FAILURE... [Pg.317]

Foody JM, Farrell MH, Krumholtz H Beta blocker therapy in heart failure. JAMA 2002 287 883. [PMID 11851582]... [Pg.318]

In the past, beta blockers were considered detrimental in patients with heart failure.60 As indicated in Chapter 20, these drugs decrease heart rate and myocardial contraction force by blocking the effects of epinephrine and norepinephrine on the heart. Common sense dictated that a decrease in myocardial contractility would be counterproductive in heart failure, and beta blockers were therefore contraindicated in heart failure.60,69 It is now recognized that beta blockers are actually beneficial in people with heart failure because these drugs attenuate the excessive sympathetic activity associated with this disease.56,64 As indicated earlier,... [Pg.340]

The side effects and problems associated with beta blockers were addressed in Chapter 20. The primary problem associated with these drugs is that they may cause excessive inhibition of the heart, resulting in an abnormally slow heart rate and reduced contraction force. This effect is especially problematic in heart failure because the heart is already losing its ability to pump blood. Nonetheless, the risk of this and other side effects is acceptable in most people with heart failure, and this risk is minimized by adjusting the dosage... [Pg.341]

Ahmed A, Dell Italia LJ. Use of beta-blockers in older adults with chronic heart failure. Am J Med Sci. 2004 328 100-111. [Pg.344]

Bader FM, MacGregor JF, Gilbert EM. Initiation and use of beta-blockers in class IV heart failure. Curr Heart Fail Rep. 2004 1 72-76. [Pg.344]

Jafri SM. The effects of beta blockers on morbidity and mortality in heart failure. Heart Fail Rev. 2004 9 115-121. [Pg.345]

Beta-Blockers That Have Reduced Mortality in Heart Failure Bisoprolol (Zebeta, unlabeled use)... [Pg.308]

I 9 Metra M, Giubbini R, Nodari S, Boldi E, Modena MG, Dei Cas L. Differential effects of beta-blockers in patients with heart failure a prospective, randomized, double-blind comparison of the long-term effects of metoprolol versus carvedilol. Circulation 2000 102 546-551. [Pg.461]

The ongoing BETACAR study is comparing the safety and efficacy of betaxolol compared to carvedilol in heart failure [113]. The two beta-blockers appear to have similar effects on left ventricular ejection fraction [New York Heart Association (NYHA) class], exercise capacity and quality of life over 6 months [114]. However, final results are not yet available. [Pg.211]

The systemic effects exerted by eye-drops are most pronounced in the case of agonists and antagonists in the autonomic nervous system. For example, beta-blockers in eye-drops can cause bronchospasm, heart failure, syncope, and psychiatric disorders (4-6), especially at high doses and with non-selective beta-blockers, although these adverse reactions are usually related to failure to observe prescribing precautions (1). [Pg.1307]

Hu H, Jui HY, Hu FC et al (2007) Predictors of therapeutic response to beta-blockers in patients with heart failure in Taiwan. J Formos Med Assoc 106 641-648... [Pg.256]

Littlejohn MD, Palmer BR, Richards AM et al (2008) Ilel64 variant of beta2-adrenoceptor does not influence outcome in heart failure but may interact with beta-blocker treatment. Eur J Heart Fail 10 55-59... [Pg.257]

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