Beta blockers angina treatment

Knight CJ et al. Different effects of calcium antagonists, nitrates and beta blockers on platelet function Possible importance for the treatment of unstable angina. Circulation 1997 95 125-132. 

Patients should be excluded from beta-blocker treatment if they have significant cardiorespiratory diseases (asthma and other pulmonary obstructive diseases, congestive heart failures, angina), insulin-dependent di-... 

Timolol CBlocadren). This nonselective beta blocker is administered orally for the treatment of hypertension and prevention of myocardial reinfarction. It may also be used to treat angina or prevent vascular headaches. 

Alpha-adrenergic antagonists are used primarily as antihypertensive drugs because of their ability to block vascular alpha-1 receptors. Beta-adrenergic antagonists (beta blockers) are administered primarily for their inhibitory effects on myocardial function and are used in the prevention and treatment of hypertension, angina pectoris, arrhythmias, and myocardial reinfarction. Many of the drugs introduced in this chapter are discussed further in chapters that deal with the specific clinical conditions (e.g., hypertension, asthma, and other disorders). 

Spaulding C, Cabanes L, Weber S. Pharmacological and therapeutic basis for combined administration of beta blockers and calcium channel blockers in the treatment of stable chronic angina. BrJ Clin Pract Suppl. 1997 88 17-22. 

Vetrovec GW, Parker VE. Alternative medical treatment for patients with angina pectoris and adverse reactions to beta blockers. Usefulness of nifedipine. Am J Med 1986 81(4A) 20-7. 

Beta blockers are used in the treatment of hypertension, angina pectoris, supraventricular arrhythmias, supraventricular tachycardia, sinus tachycardia, ventricular tachycardia, myocardial infarction, pheochro-mocytoma, migraine headache, and essential tumor. 

Cardiovascular agents Drugs that have their action on the heart or peripheral blood vessels for the treatment of hypertension (high blood pressure), angina, heart failure, or cardiac arrhythmia (e.g., beta-blockers,... 

Atenolol - beta blocker hypertension, angina, arrhythmia Atomoxetine - CNS stimulant treatment of ADHD Atorvastatin - statin lipid lowering drug Atovaquone - antimalarial... 

Beta-adrenergic blocking agents are effective for the prophylactic therapy of exertional angina pectoris by reducing heart rate and the force of myocardial contraction. However, verapamil, nifedipine, and diltiazem are also effective for the prophylactic treatment of stable exertional angina. The combination therapy with beta-blockers and calcium-entry blockers is well tolerated, effective, and safe. 

McGourty JC, Silas JH, Solomon SA. Tolerability ofcombined treatment with verapamil and beta-blockers in angina resistant to monotherapy. PostgradMedJ 9%5) 61, 229-32. 

Ivabradine hydrochloride is marketed by Servier as treatment for Angina pectoris in patients who have an intolerance for beta-blockers. The drug contains an interesting benzocyclobutane structure that was prepared using a palladium-catalysed cyclisation reaction, which includes a CH-activation (Scheme 44) [112]. The methodology had been developed earlier by Baudoin and co-workers [113]. 

---