Bergmann, Max

Emil Fischer himself collected, and edited, the greater part of his own work in the carbohydrate field in his well-known book Untersuchungen liber Kohlenhydrate und Fermente. This volume was completed in 1908. Subsequent work was compiled under the same title by Max Bergmann, Fischer s student and faithful assistant this second volume was published in 1922. Both volumes contain a list of the titles and places of journal publication of his papers, as well as a subject index to them. The present author accordingly considers it unnecessary to cite references here. In a few instances, work is described which appeared subsequent to 1922. 

However, the first mention of a three-point contact (between a chiral drug and its receptor) is found in an article by Easson and Stedman published in 1933 16W, and a year later, Max Bergmann postulated a three-point contact (involving COjH, H2N and the dipeptide linkage) between peptidases and the dipeptides hydrolyzed by them.16c) Both these publications seem to have been overlooked subsequently I thank Professors V. Prelog and H. Hirschmann, respectively, for drawing my attention to them. 

Institute for Material Science and Max Bergmann Center of Biomaterials, Dresden University of Technology, D-01062 Dresden, Germany,... 

Institute for Material Science and Max Bergmann Center of Biomaterials... 

Leibniz Institute of Polymer Research Dresden, Max Bergmann Center of Biomaterials, Germany e-mail wemer ipfdd.de M. Valtink... 

As the last episode, a rule on the number and sequences of amino acids in the polypeptide chain of proteins should be mentioned, a result of questionable amino acid analysis of sometimes not quite homogeneous proteins. Max Bergmann and C. Niemann in 1936-1938 concluded from their analytical values... 

The Era After Emil Fischer. The Carbobenzoxy Group, Max Bergmann and His Scientific Circle... 

Plate 3. Max Bergmann (1886-1944), (Photo Archives of the Rockefeller Univ., New York)... 

As shown, a considerable part of the modern separation methods of amino acids and peptides originated in Max Bergmann s laboratory at the Rockefeller Institute. A different separation technique was introduced in the same institute at the same time by Lyman C. Craig, in the laboratory of J.A. Jacobs. Here, from 1933, he worked on ergot alkaloids developing a lasting interest in separation techniques. The well-known method of extraction of substances from an aqueous into a non-water-miscible phase like chloroform or vice versa was systematically elaborated by him to a multiple extraction and re-extraction procedure, countercurrent distribution [25]. By this method, performed in a specially... 

In parallel the search was continued for peptidases yet unidentified, in which also Emil L. Smith, later a famous authority on protein research in the U.S.A. was successfully engaged. In Germany, similar work was set forth at the Dresden Institute by Max Bergmann s successor Wolfgang Grassmann (1898-1978), and by Ernst Waldschmidt-Leitz (both students of Richard Willstatter), who after his habilitation there (1924), in 1928 left Munich to hold a chair as professor in Biochemistry at the Technische Hochschule, later at the University of Prague until 1945. After his return to Munich he was there, as professor at the University, from 1953-1963. 

---