Benzene-1,3,5-tricarboxylate

Although the chemical properties of benzene-1,2,3-tricarboxylic acid (BTCA) were first studied over 100 years ago, the crystal stmcture of BTCA was not reported until a recent powder XRD study [117]. In contrast, the crystal stmctures of several solvate phases of BTCA were determined previously, including a dihydrate stmcture and solvate stmctures containing different alcohols and other solvent molecules. The preparation of a pure (nonsolvate) crystalline phase of BTCA by crystal growth fi om solution is difficult due to the competitive formation of solvate phases. In such cases of materials that cannot be prepared as a pure (nonsolvate) phase by conventional crystal growth processes, a possible route to obtain the pure phase is to carry out desolvation of a solvate phase at elevated... 

Considering just acid-base chemistry, not ion pairing and not activity coefficients, find the pH and concentrations of species in 1.00 L of solution containing 0.040 mol benzene-1,2,3-tricarboxyl ic acid (H3A), 0.030 mol imidazole (a neutral molecule, HB), and 0.035 mol NaOH. 

Some examples for the isolation of the desired poly(trifluoromethyl) compounds from product mixtures by chemical purification have been reported. In the reaction of benzene-1,2.3-tricarboxylic acid with sulfur tetrafluoride/hydrogen fluoride a mixture of 1.2,3-tris(tri-fluoromethyl)benzene (9). 1,1,3,3-tetrafluoro-4-(trifluoromethyl)-l,3-dihydroisobenzofuran... 

Secondly, the transport inhibitor must be able to pass the cell membrane. The inability of benzene-1,2,3-tricarboxylate to inhibit gluconeogenesis from lactate in perfused pigeon liver, a tissue in which mitochondrial efflux of phosphoenolpyruvate is obligatory for glucose synthesis, is presumably due to lack of penetration through the plasma membrane [16], This observation is interesting since it shows that the ability of an inhibitor to penetrate the cell membrane may vary from tissue to tissue benzene-1,2,3-tricarboxylate does inhibit lipogenesis in hepatocytes of neonatal chicks, as discussed above. Another example is the apparent relative impermeability of the plasma membrane of isolated foetal rat hepatocytes, as compared with that from adult rats, for atractyloside, the inhibitor of the adenine nucleotide translocator [17]. 

Polymeric compounds are formed from 1,3,5-benzene tricarboxylate and zinc with 2,2 -bipyridyl, phenanthroline, or a pyridyl-2-(l-methyl-lH-pyrazol-3-yl) derivative. A number of compounds were characterized with varying ligand protonation and some, such as [ZnL(pyridine-2-(l-methyl-4-nitro-lH-pyrazol-3-yl))(H20)], containing single-stranded coordinative chains.383... 

Furthermore, an observed change in the coordination of the carboxylate ligands from benzene tri-carboxylic [57] likely involves a second N02 molecule and leads to the formation of a monodentate nitrate bound to the copper (see reaction (10.2)). This rearrangement may cause the appearance of carboxylic groups on the benzene tricarboxylic linkage and the formation of NO, which is released in each case during N02 adsorption process in dry conditions (see reaction (10.3)). 

Table 5.1 presents some values for the intrinsic binding constants, and also pair and triplet correlations for benzoic acid, benzene dicarboxylic acids, and benzene tricarboxylic acids. 

Before speculating on the origin of the nonaddivity in the tricarboxylic acid, we note that the pair correlation in the cyclohexane-triamine is much stronger than the corresponding pair correlation in benzene-tricarboxylic acid—probably due to the shorter distances between the protons in the former. Furthermore, the nonaddi-... 

Figure 14.24 Templation of a covalent polymer (PMMA) by a supramolecular metallogel of iron(III) benzene tricarboxylate (BTC) (reproduced by permission of The Royal Society of Chemistry).

Another example is the adsorption of prochiral 1,2,4-benzene tricarboxylic acid on Cu(100). As determined via X-ray absorption studies, this molecule has a tilted local geometry on the surface. The adsorbate complex is therefore chiral [70]. The long range ordered adlattice, however, has p(3 x 3) periodicity i.e., the molecules are strictly aligned by the quadratic substrate mesh. 

Figure 1 Examples of two topologically distinct isoreticular MOF structures, (a) A cubic fragment of IRMOF-1. Each corner of the cubes is built up of a connector (b) and linked by a linker (c) (here 1,4-benzenedicarboxylate). The linkers form the edges of the cube. The connector can be described as four distorted tetrahedra Zn(01)30 connected by a central 02. (d) A cubic fragment of Cu-BTC (Cu3(BTC)2(H20)3 BTC 1,3,5-benzene-tricarboxylate) The structure is built up of the so-called paddle-wheels (e). Each metal atom completes its pseudo-octahedral coordination sphere, Cu(COO)2, with an aqua ligand.

In the present work we show the results of a systematic study and give an overview over the properties of a wide range of isoreticular metal-organic frameworks. First results of calculations with an exchanged metal atom (Cu) in the connector are presented as well (Cu3(BTC)2(H20)3 BTC 1,3,5-benzene-tricarboxylate in the following will be used Cu-BTC). For a more detailed study the reader is referred to Ref. 18. 

Still and Yoon [70] synthetized an A4B6 cyclo-oligomer from 1,3,5-benzene tricarboxylic acid (A) and (R,R)-l,2-diaminocyclohexane (B). This synthesis yielded two isomers with tetrahedral or D2 symmetry. Further studies proved the capability of the Da-symmetrical isomer to recognize selectively L-amino acids (70-90% ee), and to discriminate between different side chains of amino acids according to their size (phenyl > benzyl, ethyl > methyl) [71]. 

Tbe next mejor comasereial success was the family of composite membranes. They feature a very thin RG membrane on a suitable substrate, usually a UF membrane. Most of the RO composite membranes are polyamide cnatings in which the separating layer is produced by interfacial polymerization of a diamine and a multibasic acid chloride. The most snecessfol recent memhrane is based on an inteifacial polymer of 1,3-diamino benzene and 1,3,5-benzene tricarboxylic acid chloride coated on a polysulfone membrane substrate. 

ADK CIZER C-8 1,2,4-Benzenetricarboxylic acid, trioctyl ester Benzene tricarboxylic acid, trioctyl ester Diplast TM Diplast TM8 EINECS 201-877-4 HSDB 5263 JayBex TOTM Kodaflex TOTM Nuopiaz 6959 PX 338 TOTM Tri (2-ethylhexyl) trimellitate Tri-n-octyl trimellitate Trimex N 08 Trioctyl trimellitate Nuopiaz TOTM Palatinol TOTM Plasthall TOTM PX-338 Staflex TOTM Uniflex TOTM. Plasticizer Solid d = 0.989 bp = 414°. Exxon ExxonMobil Chem. Co. 

Herbstein EH (1996) 1,3,5-Benzene-tricarboxylic acid. In Atwood JL MacNicol DD, VOgtle F, Lehn JM (eds) Comprehensive Supramolecular Chemistry, Vol 6. Pergamon, New York, p 61... 

An unsuccessful attempt to obtain this formula was made by substituting a certain amount of the terei thalic acid with trimesinic acid (13,5-benzene tricarboxylic acid) or by using carboxylated compounds having higher acidity due to habgen atoms present in the a-position with respect to the carboxylic groups ... 

Another long-known example of 2D inclined interpenetration is the structure of trimesic acid (1,3,5-benzene-tricarboxylic acid). It contains hydrogen-bonded (6.3) sheets that interpenetrate such that each window of each sheet is penetrated by three other inclined sheets. It is also possible for more than two stacks of parallel sheets to show inclined interpenetration—the remarkable structure of Co2(azpy)3(N03)4-Me2CO-3H20 [a /73 =4,4 -azo/ zT-(pyridine)] contains four separate stacks of parallel (6,3) sheets that all interpenetrate at mutually inclined angles.Combinations of network and interpenetration topologies are also possible. Inclined interpenetration between (4,4) and (6.3) sheets has been reported,and... 

---