Benzamide 2,6-dichloro

Chloro-4-nitrophenylamide-6-chlorosalicylic acid. 2, 5-Dichloro-4 -nitrosalicylanilide. 2-Hydroxy-5-chloro-/V-(2-chloro-4-nitrophenyl) benzamide. 5-Chloro-7V-(2,-chloro-4 -nitrophcnyl)-2-hydroxybcnzamide. 5-Chloro-2 -chloro-4 -nitrosalicylanilide. 

Dichloro-N-(L 1-dimethyl-2-propynyl) benzamide (pronamide, Kerb )... 

V-(3,5-dichloro-4-pyridyl)-4-methoxy-3-(prop-2-ynyloxy)benzamide. Abbreviation. ND, not determined. 

U-594494A, chemically ( )-cis-3,4-dichloro-A/ -methyl-JV-[2-(l-pyrrolidinyl)cyclohexyl]-benzamide (67), is a potent, long-acting anticonvulsant without sedative or analgesic effects (263). It is not only effective in antagonism of electroshock seizures, but also effective against excitatory amino acids and... 

It was found that two active metabolites, cj5-A7-(2-aminocyclohexyl)-3,4-dichloro-benzamide (67a) and cis-N-(2-methylamino-cyclohexyl)-3,4-dichlorobenzamide (67b) were formed, each of which was an active anticonvulsant (263). The individual enantiomers were recently evaluated and the (-)-isomer was metabolized to a lesser extent than, the (+)-isomer, which had a lower oral bioavailability as well (267). Fischer et al. independently evaluated U-54494A (268). It was observed in this study that there was considerable evidence to suggest that the stimulation of K-receptors reduces the entry of Ca + into neurons or nerve terminals, which may be related to the closure of N-typeCa channels. This action can result in a decrease of neuronal excitability and a reduction of transmitter release (269-271). Fischer concluded that it was thus difficult to draw definitive conclusions regarding the involvement of central K-opioid receptor mechanisms in the anticonvulsant actions of U-54494A (268). 

The herbicidal properties of alkynyl benzamides were described by Perrot (1969), Viste et al. (1970), and Sumpter et al. (1970). The most active member of this group is 3,S-dichloro-N-(l,l-dimethylpropynyl)benzamide (34), known by the common name propyzamide (in the USA pronamide). 

Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxy-phenyl)-6-hydroxy- Benzanilide, 2,2 -dihydroxy-3,3, 5,5, 6-pentxhloro- BRN 2014120 CCRIS 5744 2,2 -Dihydroxy-3,3, 5,5, 6-... 

Pentxhloro-2 -hydroxysalicylanilide Salicylanilide. 3,3 ,5,5, 6-pentachloro-2 -hydroxy- 2,3,5Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-benzamide Zanil Zanilox. A vetrinary anthelmintic (Trematodes). Used in combination with Haloxon. Solid mp = 209-211°. 

Benzamide, 3,5-dichloro-N-(1,1-dimethyl-2-propynyl)- BRN 0882391 Caswell No. 306A CCRIS 1413 Cianex 3,5-Dichloro-N-(1,1 -dimethyl-2-propynyl)benzamide 3,5-Dichloro-N-(1,1 -... 

Drach and co-workers prepared 4,5-(diarylthio)-2-phenyloxazoles 1638 from p,p-dichloro-a-(toluenesulfonyl)benzamide 1636 (Scheme 1.420). The intermediate Af-[l,2,2-tri(arylthio)ethenyl]benzamides 1637a and 1637b were isolated in excellent yield and were characterized spectroscopically. Cyclization of 1637 to 1638 was accomplished in modest yield. 

Zoxamide (1) [3,5-dichloro-N-(3-chloro-l-ethyl-l-methyl-2-oxopropyl)-4-methyl-benzamide, RH-7281, Fig. 16.1.1] was discovered and commercialized by Rohm and Haas Company in 2001 for control of Oomycete pathogens [1], and is now marketed by Dow AgroSciences LLC. The primary markets for zoxamide are late blight on potatoes and downy mildews on vines and vegetables. Inhibitors of microtubule assembly that have been used as fungicides include the benzimidazole (BZ) and thiophanate fungicides such as carbendazim and thiophanate-methyl, the N-phenylcarbamate (NPC) diethofencarb, and the antibiotic griseofulvin. Zoxamide represents the first inhibitor of microtubule assembly to be used commercially for control of Oomycetes. 

Dichloro-N- [3-chloro-5-(trifluoromethyl)-2-pyridinyl] methyl benzamide... 

Synonyms 3,5-Dichloro-N-(3,4-dichlorophenyl)-2-hydroxy benzamide 3,3, 4, 5-Tetrachlorosalicylanilide... 

You et al. investigated the enantioselective chlorocyclisation of indole-derived benzamides for the synthesis of spiro-indolines and fused indo-lines. (DHQD)2PHAL was used as catalyst, and DCDPH or l,3-dichloro-5,5-dimethylhydantoin (DCDMH) as chlorine source. 

Synonyms Clanex 3,5-Dichloro-7V-(l,l-dimethylpropynyl)benzamide 3,5-Dichloro- -(l,l-dimethyl-2-propynyl)benzamide Kerb Kerb SOW Promamide Pronamide RCRA waste number U192 RH-315. 

Thianthrene-di-, tri-, and tetracarboxylic acids, and a variety of their derivatives, were prepared and polymerized with co-monomers to obtain thianthiene-containing polyimides, aramids and polybenzoxazoles. The multiply substituted thianthrene derivatives were prepared starting with dichloro-substituted benzamide or phthalimide via chlorine displacement by sulfur nucleophiles. The protected carboxyl groups enhanced the displacement reaction to give thianthrene bisamides and imides in good yields. Deprotection with base gave carboxylic acid derivatives. 

With N2H2 at -15°C (230) yields benzamide (231) which cyclises in the presence of NaOMe/MeOH to (232) (74%). The similar reaction of (230) with PhNHNH2 gives (233) (70%). NjN-dichloro-p-toluene suiphonardde, (TSNCI2) adds to phenanthrene... 

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