Neoplasms benign

Fibroadenoma A benign neoplasm derived from glandular epithelium that commonly occurs in breast tissue. 

Benign prostatic hyperplasia (BPH), a nearly ubiquitous condition, is the most common benign neoplasm of American men and occurs as a result of androgen-driven prostate growth. 

Dibromoethane is a potent carcinogen in rats and mice, causing malignant and benign neoplasms of epithelial and mesenchymal origin in multiple organ systems when administered by inhalation, oral, or dermal routes. Cancer was also induced at initial point of contact with... 

A significant increase in endometrial stromal polyps, a benign neoplasm, occurred in female mice administered up to 3.3g/kg/day... 

No significant effects on reproductive function or pregnancy outcome were found in two-generation reproduction smdies in rats at doses that were toxic, causing hyperkeratosis and benign neoplasms of the forestomach. ... 

Epidemiological studies of benign neoplasms, presumed preneoplastic lesions and other end-points thought to be relevant to cancer are also reviewed by working groups. They may, in some instances, strengthen inferences drawn from studies of cancer itself... 

Huff, J.E., Eustis, S.L. Haseman, J.K. (1989) Occurrence and relevance of chemically induced benign neoplasms in long-term carcinogenicity studies. Cancer Metastasis Rev., 8, 1-21... 

Dobyns BM, Sheline GE, Workman JB, Tompkins EA, McConahey WM, Becker DV. Malignant and benign neoplasms of the thyroid in patients treated for hyperthyroidism a report of the cooperative thyrotoxicosis therapy follow-up study. J Clin Endocrinol Metab 1974 38(6) 976-98. 

Table 12.1 Some General Characteristics of Malignant and Benign Neoplasms ...

Better standardization of pathology evaluations is needed (e.g., distinguishing hyperplasia from benign neoplasms)... 

Hepatic adenomas, benign neoplasms consisting of hepatocytes, appear to be linked to the use of oral contraceptives, and before 1960 were rarely described. The incidence of hepatic adenomas has since increased, reflecting increased use of oral contraceptives, and in 1977 was estimated at five cases per million women aged 15-45 years. Hepatic adenomas have been detected in patients taking the pill continuously for a period of six months to four years [15]. To date, mestranol has been the constituent predominantly implicated [12]. 

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