BC-gelatin

Fig. 9 Pictures of BC, gelatine, and BC-gelatine DN gels, a before compression, b during compression, c after 10 min compression, d SEM images of the stratified structure. Reprinted with permission from [53]...

The morphologies of DN gels under one million cycles of friction, which is equivalent to 50 km of friction (50 x 10 mm), are shown in Fig. 23. The maximum wear depth of the PAMPS/PAAm, PAMPS/PDMAAm, BC/PDMAAm, and BC/gelatin gels was 9.5, 3.2, 7.8, and 1302.4pm, respectively. It is amazing that the maximum wear depth of PAMPS/PDMAAm DN gel is similar to the value of UHMWPE (3.33 pm). In addition, although the maximum wear depth of... 

Table 1 The average values of the water content, and the material properties concerning the PAMPS/PAAm DN gel, PAMPS/PDMAAm DN gel. BC/PDMAAm DN gel, and BC/Gelatin DN gel, which were used in the wearing study. (Reproduced, with permission, from the literature [106])...

DN gels PAMPS/PAAm PAMPS/PDMAAm BC/PDMAAm BC/Gelatin... 

Fig. 25 Histological observations at 4 weeks (HE stain, 2x). (a) Negative control (high density polystyrene), (b) Positive control (polyurethane containing 0.75% zinc diethyldithiocaibamate), (c) PAMPS/PDMAAm gel, (d) PAMPS/PAAm gel, (e) BC/PDMAAm gel, (f) BC/gelatin gel. Scale bar is 1 mm. (Reproduced, with permission, from [108])...

For the BC-gelatin composite synthesized by impregnation with a gelatin solution and cross-linked with l-ethyl-3-[3-dimethylamino... 

By supplementing a gelatin solution in the culture medium, gelatin was well incorporated into the BC nanofibril structure and filled the pores, leading to a denser structure of the BC-gelatin... 

Figure 14.4 SEM images of films in re-swollen form of BC (a) and BC-gelatin prepared by addition of 10% w/v gelatin in the culture medium [b).

Because of the hydrophilicity of gelatin, the WAC of the BC-gelatin composite and the BC-gelatin/cross-linkers improved with increasing concentrations of gelatin [18,57]. Because of this, gelatin was able to disrupt the crystallization of BC by inserting between cellulose molecules [28]. Nonetheless, the randomized and weak structure of the composite would likely decrease its WAC [57]. 

By comparing with BC film, the denser film with a smaller pore size was formed by the supplementation of gelatin into BC culture medium. Water molecules hardly penetrated through the small pores of the BC-gelatin composite film, resulting in the reduction of theWVTR [57]. 

For specific applications [e.g., bone tissue engineering], BC-gelatin/PA doped with hydroxyapatite [HAp] were synthesized [BC-gelatin/PA/Hap]. The cell compatibility of BC-gelatin/PA/HAp was tested with mesenchymal stem cells [58]. The results indicated that the composite supported cell growth and proliferation, over 7 days of cultivation. Studies on the effectiveness of composites in vitro and in vivo behavior should be further explored. 

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