Basket cell

Somogyi, J., Baude, A., Omori, Y. et al. GABAergic basket cells expressing cholecysokinin contain vesicular glutamate transporter type 3 (VGLUT3). Eur J. Neurosci. 19 552-569,... 

Both anandamide and 2-AG are inactivated by enzymatic hydrolysis (Goparaju et al. 1998). Fatty acid amide hydrolase (FAAH) is an enzyme that catalyses their hydrolysis. High concentrations of FAAH were found in the cerebellum, hippocampus and neocortex of rat brain, which are also rich in cannabinoid receptors. Further, there is a complementary pattern of distribution of FAAH and the CBl receptor. For example, in the cerebellum, FAAH is found in the cell bodies of Purkinje cells and the CBl receptor is found in the axons of granule cells and basket cells, which are presynaptic to Purkinje cells. 2-AG may also be inactivated by direct esterification into membrane phospholipids. Cannabinoid Receptors... 

Hippocampus Pl,P2 a2 Excitation of pyramidal neurons. Induction of LTP. Inhibition of GABA basket cells Emotional memory. Fear conditioning and extinction. 

Neu, A., Foldy, C., and Soltesz, I. (2007). Postsynaptic origin of CBl-dependent tonic inhibition of GABA release at cholecystokinin-positive basket cell to pyramidal cell synapses in the CA1 region of the rat hippocampus.. Physiol. 578, 233—247. 

Somogyi, J., Baude, A., Omori, Y., Shimizu, H., El Mestikawy, S., Fukaya, M., Shigemoto, R., Watanabe, M., and Somogyi, P. (2004). GABAergic basket cells expressing cholecystokinin contain vesicular glutamate transporter type 3 (VGLUT3) in their synaptic terminals in hippocampus and isocortex of the rat. Eur.J. Neurosci. 19, 552-569. 

Frotscher M (1985) Mossy fibres foim synapses widi idendfied pyramidal basket cells in die CA3 region of die guinea-pig hippocampus A combined Golgi-elecfion microscope study. J Neurocytol 14 245-259. 

Ekstrand JJ, Domroese ME, Feig SL, Illig KR, Haberly LB. 2001a. Immunocytochemical analysis of basket cells in rat piriform cortex. J Comp Neurol 434 308-328. 

Glutamate is a key neurotransmitter in the cerebellum mossy fibres onto granule cells parallel fibres onto Purkinje and stellate/basket cells, climbing fibres onto Purkinje cells, and also mossy fibre and climbing fibre inputs onto Golgi cells all use glutamate (Fig. 19) (Voogd... 

In the hippocampus, CBi receptors are localized presynaptically in GABA axon terminals, most of which originate from CCK-positive basket cells (Katona et al. 

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