Basilar thrombosis

Additional common sites for atherosclerotic occlusion include the origin of the vertebral artery, the distal vertebral and vertebrobasilar junction, the midbasilar artery, and the proximal PCA. Unlike ICA disease, severe atherosclerotic stenosis in the distal intracranial vertebral and basilar arteries can cause stroke via thrombotic occlusion of local branches as well as artery-to-artery embolus to the top of the basilar artery or the PCA(s). Low flow in the basilar artery can lead to thrombus formation with occlusion of one brainstem penetrator vessel after another. Basilar thrombosis is not rare and is fatal because brainstem function is completely dependent on this vascular supply [20, 23]. 

Coma, may be associated with absent eye movements simulating basilar thrombosis... 

Junghans U, Seitz RJ, Wittsack HJ, Aulich A, Siebler M. Treatment of acute basilar artery thrombosis with a combination of systemic alteplase and tirofiban, a nonpeptide platelet glycoprotein Ilb/HIa inhibitor report of four cases. Radiology 2001 221 795-801. 

Suggested Alternatives for Differential Diagnosis Meningitis, basilar artery blood clots (thrombosis), cardioembolic stroke, cavernous sinus syndromes, cerebral venous blood clots (thrombosis), confusional states and acute memory disorders, epileptic and epileptiform encephalopathies, febrile seizures, haemophilus meningitis, intracranial hemorrhage, leptomeningeal carcinomatosis, subdural pus (empyema), or bruise (hematoma). 

Unlabeled Uses Acute peripheral occlusive disease, basilar artery occlusion, cerebral infarction, deep vein thrombosis, femoropopliteal artery occlusion, mesenteric or subclavian vein occlusion, pleural effusion (parapneumonic)... 

In most patients with BA thrombosis, obstruction is limited to the mid portion of the basilar artery (Fig. 1.2) (Voetsch et al. 2004). Embolic occlusion rather than thrombotic occlusion mainly blocks the distal part of the BA when it divides into the PCAs. The distal BA supplies the midbrain and... 

Fig. 1.2. Digital subtraction angiography of a patient with basilar artery thrombosis before (left) and after (right) thrombolytic therapy. (Courtesy of Prof, von Kummer)...

Doehn C, Buttner H, Fornara P, Jocham D. Fatal basilar artery thrombosis after chemotherapy for testicular cancer. Urol Int 2000 65(l) 43-5. 

Davis SM, Donnan GA (2006) Basilar artery thrombosis recanalization is the key. Stroke 37 2440... 

Carotid Artery Stenosis 131 Basilar Artery Occlusions 132 Intracranial Aneurysms 133 Cerebral Venous Thrombosis 134... 

SM and polysaccharide sulphate (PSS) inhibit the adhesion of erythrocytes, from patients with ceidrral thrombosis, to cultured human umbilical vein endothelial cells (HUVEC) (25). Treatment of SM, PSS, dextran 40 and mannitol improve the viscoelasticity properties of red blood cell suspension (31). SM inhibits the contraction of rai it basilar artery rings evoked by CaCh... 

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