Barton, Sir Derek

Barton, Sir Derek Harold Richard (1918-98) English chemist who became noted when he wrote an influential paper on the... 

Balmer, Johann J., 133 Baltimore, David, 133 Bamberger, Eugen, 133 Barbiturate, 201 Bardeen, John, 181 Barger, George, 133 Bartlett, Neil, 133, 215 Bartlett, Paul D., 133 Barton, Sir Derek H.R, 133-134, 154, 236 Bases, 131, 178, 220,237 Battery, 145,193-194, 202, 220 see also Leyden jar Voltaic pile... 

Hassel shared the 1969 Nobel Prize in chemistry with Sir Derek Barton of Imperial College (London) Barton demonstrated how Hassel s structural results could be extended to an analysis of conformational effects on chemical reactivity... 

Sir Derek BARTON (Texas, U.S.A.) Christiane BONNELLE (Paris, France) Paul CARO (Meudon, France)... 

Sir Derek H. R. Barton (1918-1998, formerly Distinguished Professor of Chemistry at Texas A M University) and Odd Hassell (1897-1981, formerly Chair of Physical Chemistry of Oslo University) shared the Nobel prize in 1969 for developing and applying the principles of conformation in chemistry. Their work led to fundamental understanding of not only the conformations of cyclohexane rings, but also the structures of steroids (Section 23.4) and other compounds containing cyclohexane rings. 

When Professor Atta-ur-Rahman informed me, many years ago, of his desire to launch a new series which would become Studies in Natural Products Chemistry, I enthusiastically encouraged him to do so but pointed out what a difficult task it would be. First, the expert authors able to write the very numerous chapters of such a work would have to be found. Then, a logical sequence to the series would have to be determined. Finally, because a large number of books, reviews etc. already exist which dealt with particular areas of the chemistry, biology and therapeutic applications of natural products (in particular, Sir Derek Barton s posthumous Comprehensive Natural Products Chemistry ), something new would have to be offered. 

S. Hanessian Recent studies in synthetic carbohydrate chemistry Sir Derek Barton New and selective reactions and reagents... 

Sir Derek Barton and W. David Ollis, "Comprehensive Organic Chemistry", Vol. 5, Pergamon Press, Oxford, London (1979). 

There have been several detailed analyses of the early development of conformational analysis169,170 and a short historical review dedicated to one of the key participants, Sir Derek Barton.171 Charlotte Roberts, a young woman teacher who took a doctoral degree in the subject at Yale and wrote a textbook on stereochemistry in 1896, has been profiled.172 The now outdated screw theory of Moeller features in a paper on stereochemistry and the ether .173... 

Finally, in this past year, two of this century s giants of stereochemistry passed away. However, the scientific legacies of Vladimir Prelog and Sir Derek H. R. Barton are firmly embodied in the fundament of our knowledge of stereochemistry and their personal legacies irrevocably woven into the hearts and minds of those co-workers, colleagues, students and friends who were graced by their lives. 

Over the years we benefited from visits by many consultants, but it was the Professors I referred to as the three great B s of our chemistry who stimulated us the most. These were Professors Paul A. Bartlett (University of California, Berkeley), Professor Sir Derek H. R. Barton (Imperial College, London, and Texas A M, State College), and Professor Ronald Breslow (Columbia University, New York). They each brought different qualities to aid us in our work. 

Dr. Ashit Ganguly with Professor Sir Derek Barton... 

It was a desire to explain the reactions of steroids that led Sir Derek Barton (1918-98) to drseover, in the 1940s and 1950s, the principles of conformational analysis described in this chapter. It was forthis work that he shared the Nobel prize in 1969. We will come back to steroids in more detail in Chapter 51. 

Animals ex adrenal cortex semisynthesis by Sir Derek Barton (UK, Nobel Prize, Chemistry, 1969, organic chemical conformation)... 

---