Barton, Derek

Backbone (protein), 1028 Backside displacement. reaction and.363-364 von Baeyer, Adolf, 113 Baeyer strain theory, 113-114 Bakelile, structure of, 1218 Banana, esters in, 808 Barton, Derek, H. R., 389 Basal metabolic rate, 1169 Basal metabolism. 1169-1170 Base, Bronsted-Lowry, 49 Lewis, 57, 59-60 organic, 56-57 strengths of, 50-52 Base pair (DNA), 1103-1105 electrostatic potential maps of. 

Library of Congress cataloguing in publication data Barton, Derek, Sir, 1918-... 

Barton, Derek H. R. (1918-1998). An English organic chemist who won the Nobel Prize for chemistry in 1969 with Hassel. The field of conformational analysis in organic chemistry was initiated through his research in the terpene and steroid fields. He did extensive research in the area of carbanion autoxidations. He was instrumental in research concerning the relationship of molecular rotation to structure in complex organic molecules. His education took place in London, France, and Ireland. 

Synthesis of 10(S)-methylcodeine and 10(S)-methylmorphine Arzeno, Humberto B. Barton, Derek H. R. Davies, Stephen G. Lusinchi, Xavier Meunier, Bernard Pascard, Claudine... 

Barton, Derek Harold Richard FRS (1918-98) A British chemist noted for his contribution to the pyrolysis of chlorinated hydrocarbons and many other areas of organic chemistry. After gaining his doctomte from Imperial College, London, he held many academic positions and visiting professorships including Re us professor of chemistry at... 

Hassel shared the 1969 Nobel Prize in chemistry with Sir Derek Barton of Imperial College (London) Barton demonstrated how Hassel s structural results could be extended to an analysis of conformational effects on chemical reactivity... 

Anti periplanar geometry for E2 reactions is particularly important in cyclohexane rings, where chair geometry forces a rigid relationship between the substituents on neighboring carbon atoms (Section 4.8). As pointed out by Derek Barton in a landmark 1950 paper, much of the chemical reactivity of substituted cyclohexanes is controlled by their conformation. Let s look at the E2 dehydro-halogenation of chlorocyclohexanes to see an example. 

Derek H.R. Barton and Odd Hassel development of the concept of conformation and its application in chemistry... 

Selected Papers of Derek H. R. Barton by Derek H. R. Barton... 

Sir Derek BARTON (Texas, U.S.A.) Christiane BONNELLE (Paris, France) Paul CARO (Meudon, France)... 

Sir Derek H. R. Barton (1918-1998, formerly Distinguished Professor of Chemistry at Texas A M University) and Odd Hassell (1897-1981, formerly Chair of Physical Chemistry of Oslo University) shared the Nobel prize in 1969 for developing and applying the principles of conformation in chemistry. Their work led to fundamental understanding of not only the conformations of cyclohexane rings, but also the structures of steroids (Section 23.4) and other compounds containing cyclohexane rings. 

Barton, D. H. R. Crich, D. Motherwell, W. B. J. Chem. Soc., Chem. Commun. 1983, 939. Derek Barton (United Kingdom, 1918—1998) studied under Ian Heilbron at Imperial College in his youth. He taught in England, France and the US. Barton won the Nobel Prize in Chemistry in 1969 for development of the concept of conformation. He passed away in his office at the University of Texas at Austin. 

Barton, D. H. R. Beaton, J. M. Geller, L. E. Pechet, M. M. J. Am. Chem. Soc. 1960, 82, 2640. In 1960, Derek Barton took a vacation in Cambridge, Massachusetts he worked in a small research institute called the Research Institute for Medicine and Chemistry. In order to make the adrenocortical hormone aldosterol. Barton invented the Barton nitrite photolysis by simply writing down on a piece of paper what he thought would be an ideal process. His skilled collaborator. Dr. John Beaton, was able to reduce it to practice. They were able to make 40 to 50 g of aldosterol at a time when the total world supply was only about 10 mg. Barton considered it his most satisfying piece of work. 

Among the recent outstanding contributions to the chemistry of natural products is the conformational analysis designed by Derek Barton. He used it for the structural determinations of many complex molecules such as P-amyrin and cycloartenol. Robert B. Woodward was involved in the structural determinations of penicillin, strychnine, patalin, terramycin, aureomycin and the synthesis ofVitamin B12. 

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