Balance imbalance effects

Crystal surfaces. Crystal surfaces may be viewed as vast defects inasmuch as the lattice forces are incompletely balanced. The effects of this imbalance are partially offset by distortion of the crystal lattice near the surface, but crystal surfaces still show a strong tendency to adsorb other... 

Biological Antioxidant Models. Tea extracts, tea polyphenol fractions, and purified catechins have all been shown to be effective antioxidants in biologically-based model systems. A balance between oxidants and antioxidants is critical for maintenance of homeostasis. Imbalances between free radicals and antioxidants may be caused by an increased production of free radicals or decreased effectiveness of the antioxidants within the reaction system. These imbalances can be caused by the radicals overwhelming the antioxidants within the system, or by an excess of antioxidants leading to a prooxidant functionaHty (105—118). When antioxidant defense systems are consistently overwhelmed by oxidative reactions, significant damage can... 

Assembly errors are not simply the additive effects of tolerances, but also include the relative placement of each part s center of rotation. For example, a perfectly balanced blower rotor can be assembled to a perfectly balanced shaft and yet the resultant imbalance can be high. This can happen if the rotor is balanced on a balancing shaft that fits the rotor bore within 0.5 mil (0.5 thousandths of an inch) and then is mounted on a standard cold-rolled steel shaft allowing a clearance of over 2 mils. 

Dynamic imbalance is any imbalance resolved to at least two correction planes (i.e., planes in which a balancing correction is made by adding or removing weight). The imbalance in each of these two planes may be the result of many imbalances in many planes, but the final effects can be characterized to only two planes in almost all situations. 

Hypothermia—Indirect cryodestruction Metabolic uncoupling Energy deprivation Ionic imbalance Disruption of acid-base balance Waste accumulation Membrane phase transitions Cytoskeletal disassembly Frozen State—Direct cryodestruction Water solidification Hyperosmolality Cell-volume disruption Protein denaturation Tissue shearing Intracellular-ice propagation Membrane disruption Microvascular Thawed State Direct effects... 

I suppose that some ingenious minds will be able to find a way of accommodating the chemical-balance hypothesis to these data, but I suspect that the accommodation will require convoluted circumventions, like those used by the Flat Earth Society in their efforts to maintain their defunct theory in the face of photographic evidence from space. If depression can be equally affected by drugs that increase serotonin, drugs that decrease it and drugs that do not affect it at all, then the benefits of these drugs cannot be due to their specific chemical activity. And if the therapeutic benefits of antidepressants are not due to their chemical composition, then the widely proffered chemical-imbalance theory of depression is without foundation. It is an accident of history produced serendipitously by the placebo effect. 

Because the various transmitter systems in the brain are directly and indirectly linked together, purely catecholaminergic or purely serotoninergic depressions are unlikely. Furthermore, the majority of antidepressants known today have multiple effects, especially after repeated administration, and thus affect a number of transmitter systems. This fact is taken into account by more recent hypotheses of depression in that a balance between several transmitter systems is postulated as a prerequisite for mental health, whereas affective psychoses are believed to be a reflection of an imbalance. 

The most serious side effects of diuretics are fluid depletion and electrolyte imbalance.13,88 By the very nature of their action, diuretics decrease extracellular fluid volume as well as produce sodium depletion (hyponatremia) and potassium depletion (hypokalemia). Hypokalemia is a particular problem with the thiazide and loop diuretics, but occurs less frequently when the potassium-sparing agents are used. Hypokalemia and other disturbances in fluid and electrolyte balance can produce serious metabolic and cardiac problems and may even prove fatal in some individuals. Consequently, patients must be monitored closely, and the drug dosage should be maintained at the lowest effective dose. Also, potassium supplements are used in some patients to prevent hypokalemia. 

Focusing repair efforts to the source of the machine problems via vibration diagnoses so that repairs are effective and efficient. One service request for the vibration technicians involved a 200-H.P. motor-driven, induced-draft fan. An area maintenance crew considered sending the large motor to a repair shop because they were unable to get the system to operate smoothly. The vibration technician diagnosed the problem as a simple imbalance in the fan, which was corrected easily with balance weights. 

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