Azine intermolecular bonds

The reactivity of cage-annulated carbene (53) was found to depend markedly on the method of its formation." Pyrolysis of the corresponding tosylhydrazone sodium salt gave products of intramolecular CH insertion or H-abstraction. Photolysis of a diazirine precursor gave only azine products by reaction of the carbene with the precursor or diazo compound. Treatment of the m-dibromoalkane with BuLi gave products due to intermolecular insertion of the carbene into CH bonds of the solvent. 

Metal chelates are preser t in the complexes of Schiff bases of amino-(X = NR2), hydroxy- (X = O), and mercapto- (X = S) derivatives of monoheteroaromatic five-membered systems, azoles, and azines. A few publications on the complexes of azomethines of the monoheteroaromatic five-membered systems have appeared only recently. The X-ray structural study of copper(II) bis(2-N-n-octyliminomethyl)benzo[ 7]thio-phene-3-olate) 199 (04ZNK1696) is interesting in the sense that its square-planar structure is complemented by an extended octahedral one due to the intermolecular contacts of the thiophene sulfur with the copper site. Among the azole complexes, azomethine derivatives of p3Tazole (Equation (32)) prevail (05RCR193). There are several types of coordination units (N,N-, N,0-, N,S-, N,Se-) created by variation of the donor sites X in position 5 of the pyrazole ring. When X = O, S, Se, tautomer b is realized, whereas when X = NR, tautomer a predominates (Equation (32)). However, irrespective of the type of tautomer, in the chelates the coordination units have practically equalized bonds. 

The electrostatic potential is well suited for studying the orientations of intermolecular interactions, as was discussed in Sections 4.1.1 and 4.1.2 for the particular cases of hydrogen bonding and halogen bonding. Another application is to the intermolecular interactions of unsaturated planar ring systems such as benzene, benzene derivatives, azines, and other aromatics. ... 

Bi, Zhang et al. reported a novel Cu(OTf)2-catalyzed preparation of benzox-azine derivatives from readily available Af-para-tolylamides in the presence of Selectfluor and water through the intermolecular C-H-activated dehydrogena-tive cross-coupling reaction (Scheme 8.111). The C(sp )-H bond of benzylic methyl and C(sp )-H bonds of arene were activated, and new C-C and C-O bonds were formed. The desired benzoxazine derivatives could be obtained in good to excellent yield. However, the substrates such as Af-para-tolylacetamide, 3-methyl-JV-p ra-tolylbutanamide, and 2-phenyl-M-para-tolylacetamide have... 

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