Avoidance beneficial effect

It is common when adopting the TQM philosophy to regard all human interfaces as customer-supplier interfaces. When executed wisely this can have a beneficial effect on internal efficiency and effectiveness, but there are pitfalls to avoid. In a customer-supplier chain, the expectations of the external customer can be modified with each transaction, as illustrated in Figure 1.2. 

Griseofulvin Beneficial effects may not be noticed for some time tiierefore, take the drug for die full course of dierapy. Avoid exposure to sunlight and sunlamps because an exaggerated skin reaction (which is similar to a severe sunburn) may occur even after a brief exposure to ultraviolet light. 

Table 14 can be regarded as providing a reasonable overall picture, even if the results cannot applied to any particular case. However, if the underlying principle is accepted, it becomes clear that improvements in a single stage, for example the reduction of instrument variation, has a negligible beneficial effect (if this variation was not outside the normal range ). Even if the contribution of repeatability is re-duced to zero, the cumulative uncertainty is reduced by 10% only, i.e. from 2.2 to y(0.0)2 (0.8)2 (1.0)2 + (1.5)2 = 2.0. This statistical view of errors should help to avoid some unnecessary efforts to improve, e.g., calibration. Additionally, this broad view on all sources of error may help to detect the most important ones. Consequently, without participation in proficiency tests, any method validation will remain incomplete. 

Most NSAIDs (e.g., ibuprofen, naproxen, and others) inhibit both COX-1 and COX-2 isoforms. That is, they are nonselective inhibitors of the COX enzyme system. Whereas inhibition of COX-2 is responsible for beneficial effects, inhibition of COX-1 is responsible for the most common and important adverse effects of NSAIDs. COX-2-selective inhibitors have been produced and marketed in attempts to preserve the beneficial effects of COX-2 inhibition while avoiding the deleterious effects associated with inhibition of the COX-1 enzyme. This approach has not been entirely successful, as discussed below. 

Use increased pressures or rotor speed but avoid super-cavitation by operating below a certain optimum value Optimisation needs to be carried out depending on the application. Higher diameters are recommended for applications which require intense cavitation whereas lower diameters with large number of holes should be selected for applications with reduced intensity Lower free areas must be used for producing high intensities of cavitation and hence the desired beneficial effects... 

An increased selectivity for phenol in the oxidation of benzene by H202 with TS-1 catalyst in sulfolane solvent was attributed to the formation of a bulky sulfolane-phenol adduct which cannot enter the pores of TS-1. Further oxidation of phenol to give quinones, tar, etc. is thus avoided. Removal of Ti ions from the surface regions of TS-1 crystals by treatment with NH4HF2 and H202 was also found to improve the activity and selectivity (227). The beneficial effects of removal of surface Al ions on the catalytic performance of zeolite catalysts for acid-catalyzed reactions have been known for a long time. 

The use of ozonizers for deodorizing indoor air has been discussed and evaluated with respect to potential health hazards. In a normal 40-m room, an ozone concentration of 0.1 ppm is established after 3.5 h of operation of one of these devices. Evidence on health effects was cited to support the conclusion that inhalation of the quantities of ozone produced by these air conditioners should be avoided and that certainly no beneficial effects should be attributed to ozone inhalation. 

In contrast to the beneficial effects of treatment with oximes in cases of OP intoxication, reports in the literatnre suggest that treatment of poisoning with certain anticholinesterase carbamates with some oximes should be avoided because they may actually potentiate carbamate action. Other oximes decrease carbamate toxicity. The effects observed are, in general, correlated with changes in the rates of carbamylation and decarbamylation in the presence of the various oximes . ... 

Some of the beneficial effects of fish oils after acute myocardial infarction have been attributed to an antidysr-hythmic effect on the heart (5). However, the results of a randomized trial in 200 patients with implantable cardioverter defibrillators are at variance with this the rate of cardioversion was higher in those taking fish oils 1.8 g/day than in a control group who took olive oil (6). The lack of benefit and the suggestion that fish oil supplementation may increase the risk of ventricular tachycardia or ventricular fibrillation in some patients with implantable cardioverter defibrillators can reasonably be interpreted as evidence that the routine use of fish oil supplementation in patients with implantable cardioverter defibrillators and recurrent ventricular dysrhythmias should be avoided. 

A major concern among health care providers is that the use of ineffective alternative medications can delay or postpone the use of effective conventional interventions.12 Consumers may begin to self-treat various conditions with alternative medications, hoping that these treatments will provide relief and that they can forego conventional or mainstream treatments. If the alternative treatment is not effective, however, the condition can worsen to the point where conventional treatment is no longer effective or takes much longer to achieve beneficial effects. Consumers should be counseled to avoid over-reliance on these alternative medications, and to seek conventional medical treatment if symptoms fail to resolve quickly or if they worsen during alternative medication use. 

Imipramine was first shown in 1962 to have a beneficial effect in the acute episodes of anxiety that have come to be known as panic attacks. Recent studies have shown it to be as effective as MAO inhibitors and benzodiazepines. It has also been demonstrated that SSRIs are effective in panic disorder. In some instances, benzodiazepines are preferred, as they are well tolerated and their clinical effects become evident promptly. Alternatively, if one wishes to avoid the physiologic dependence associated with chronic benzodiazepine use, SSRIs are acceptable for many patients though they require several weeks to produce full therapeutic effects. 

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