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AVENTIS PHARMA

Aventis Pharma Deutschland GmbH DI A Lead Generation Chemoinfonmatics Industriepark Hoechst, G879 65926 Frankfurt / Main Jaroslaw.Tomczak aventis.com... [Pg.674]

A number of azetidine-based compounds have been disclosed in patent applications from Aventis Pharma for CBi-modulated treatment of diseases such as obesity, Parkinson s disease, schizophrenia, respiratory and neurological diseases [330-334]. Compound (556) was specifically claimed for use in two formulation patent applications [330, 331] for a stable semi-solid composition and oral emulsion composition, respectively. The optional coadministration of an agent that activates norepinephrinergic and se-rotoninergic neurotransmission (for example, sibutramine) or dopaminergic neurotransmission was also claimed for the treatment of obesity. The optional use of a dopamine agonist (for example, levodopa) was claimed... [Pg.301]

Synthetic Medicinal Chemistry Aventis Pharma Deutschland Industriepark Hoechst 65926 Frankfurt am Main Germany... [Pg.1]

Aventis Pharma Deutschland GmbH, Industriepark Hoechst, 65926 Frankfurt, Germany. E-mail sabine.imamoglu aventis.com... [Pg.210]

The authors would like to thank Thorsten Naumann, Roy Vaz (Aventis Pharma), Gabriele Cruciani (Univ. Perugia) and Gerhard Klebe (Univ. Marburg) for stimulating discussions on several aspects of this chapter. [Pg.367]

Although no biopharmaceutical product delivered to the bloodstream via the pulmonary route has been approved to date, several companies continue to pursue active research and development programmes in the area. Amongst the leading product candidates is Exubera , an inhalable dry powder insulin formulation currently being evaluated by Pfizer and Aventis Pharma in Phase III clinical studies. The inhaled insulin is actually more rapidly absorbed than if administered subcutaneously and appears to achieve equivalent glycaemic control. While promising, final approval or otherwise of this product also depends upon additional safety studies which are currently under way. [Pg.68]

HBVAXPRO (rHBsAg produced in S. cerevisiae) Aventis Pharma Immunization of children and adolescents against hepatitis B... [Pg.442]

Carry, J.-C., Damour, D., Guyon, C., Mignani, S., Bacque, E., Bigot, A (Aventis Pharma) 2-Aminothiazoline derivatives and their use as NO-synthase inhibitors, WO 0194325. [Pg.563]

Aventis Pharma Deutschland GmbH Scientific Medical Affairs,... [Pg.2]

This work was supported by the Fonds der Chemischen Industrie and the Beil-stein-Institut zur Forderung der Chemischen Wissenschaften. S.R. and U.F. are grateful for fellowships from Merz Pharmaceuticals and Aventis Pharma Deutschland, respectively. [Pg.77]

Sinbio Pierre Fabre Aventis Pharma D -Dermik... [Pg.1016]

Hoechst Marion Roussel Aventis Pharma Hoechst Marion Roussel... [Pg.3426]

Celiprolol was first synthesized by Chemie Iinz (later known as Hafslund Nycomed Pharma) [118], and eventually inherited by what is now Aventis Pharma. With a desire to attenuate the significant hepatic first-pass metabolism [119] and prolong the approximate 3-h half-life [120] observed for acebutolol, 7, analogues were directed toward protecting the latter s amide function from metabolic attack. The metabolism of 7 is shown in Scheme 8.7, wherein the rationale for protecting this functionality becomes clear. [Pg.212]

P EP 266,730 (1986, Merrell Dow Phama) L 1997 (Aventis Pharma, Sanofi-Aventis)... [Pg.448]


See other pages where AVENTIS PHARMA is mentioned: [Pg.332]    [Pg.222]    [Pg.319]    [Pg.319]    [Pg.320]    [Pg.401]    [Pg.456]    [Pg.315]    [Pg.98]    [Pg.113]    [Pg.104]    [Pg.532]    [Pg.562]    [Pg.77]    [Pg.389]    [Pg.886]    [Pg.1016]    [Pg.1271]    [Pg.1376]    [Pg.1610]    [Pg.2020]    [Pg.2407]    [Pg.2558]    [Pg.2677]    [Pg.3055]    [Pg.3577]    [Pg.3578]    [Pg.427]    [Pg.176]    [Pg.449]    [Pg.458]    [Pg.458]   


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