Assessment strategies, chemical reactivity

The SRR strategy (Fig. 6), a phrase first introduced by Ganem, involves the development of new MCRs by systematic assessment of the mechanistic or functional role of each component in a known MCR [55]. In this method one reactant (C) is substituted for reactant (D) that displays a similar chemical reactivity mode required for condensation with A and B. By incorporation of an additional reactivity or functionality into D, the resulting MCR might be directed to a different outcome, leading to scaffold diversity [55]. 

Various strategies for the syntheses of either aliphatic or aromatic functional fluorinated monomers have been proposed in the hterature. Because of their costs, they have been involved in copolymerization with fluoroalkenes, and although a lack of basic research is noted (e.g., no assessment of the reactivity ratios), many apphed investigations have been developed. In fact, most companies producing fluorinated monomers and derivatives have solved the challenge to prepare fluorocopolymers bearing sulfonic acid side groups. Nevertheless, quite a few studies concern phosphonic acid function. Compared with direct copolymerization, the alternative to prepare fluorofunctional copolymers by chemical modification of polymers is often employed. 

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