Aspartate aminotransferase atomic structure

Aspartate aminotransferase 57s, 135s, 753 absorption spectra 749 active site structure 744 atomic structure 750 catalytic intermediates, models 752 NMR spectra 149 quinonoid intermediate 750 Ramachandran plot 61 sequence 57 transamination 742 Aspartate ammonia-lyase 685 Aspartate carbamoyltransferase 348s active sites 348 regulation 540... 

Figure 3. The segment consisting of residues Cys-192 and His-193 of the 2.8 A resolution structure of a single site mutant of aspartate aminotransferase [23]. Superimposed are the initial structure (dotted lines) obtained by fitting the atomic model to a multiple isomorphous replacement map, the structure obtained after several cycles of rebuilding and restrained least-squares refinement (thick lines), the structure obtained after simulated annealing refinement (thin lines), and the structure obtained after conjugate gradient minimization (dashed lines).

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