Cyanocobalamin ascorbic acid

See AIao Ascorbic Acid Cyanocobalamin Pyridoxine Riboflavin... 

Vitamins made by biocatalysis include cyanocobalamin (Rh6ne-Poulenc and Merck Co), vitamin A (Hoffinann-La Roche Orsat 1999), ascorbic acid firom sorbitol via, directly, ketogulonic acid (BASF), riboflavin (Hoffinann-La-Roche, BASF, and Rhone-Poulenc/Archer-Daniels), and niacinamide fi om synthetic materials (Lonza). The list includes a vitamin-like nutrient, L-camitine... 

Ncphrocaps Ascorbic acid, folate, niacinamide, thiamine mononitrate, riboflavin. pyridoxinc HC1. cyanocobalamin, calcium junlnthetialr. jnd biotin ... 

Vitamin B. (.W pyridoxine) Vitamin B See cyanocobalamin) Vitamin C (See ascorbic acid) Vitamin D (Ergocalciferol) Vitamin D5 (Chlolcalciferol)... 

The water soluble vitamins, B2(riboflavin), Biascorbic acid) provided a very interesting study. The spectra for B12 and some of its analogs were first reported by Williams et al., [58] and consist of very strong Cotton bands across almost the entire visible spectral range, Figure 3. 

Many vitamins are quite stable under normal processing conditions and present little or no stability problems in finished pharmaceutical products. These include biotin, niacin, niacinamide, pyridoxine, riboflavin, and a-tocopheryl acetate. Others that can present problems are ascorbic acid, calciferol, calcium pantothenate, cyanocobalamin, fola-cin, and retinyl esters. Overages above label claim are customarily added to vitamin formulations as a means of maintaining the claimed level of each vitamin for the expected shelf life of the products. The percent overage for a particular vitamin such as L-ascorbic acid will vary... 

Although the water-soluble vitamins are structurally diverse, they are put in a general class to distinguish them from the lipid-soluble vitamins. This cla.ss includes the B-complex vitamins and ascorbic acid (vitamin C). The term B-complex vitamins usually refers to thiamine, riboflavin, pyridoxine. nicotinic acid, pantothenic acid, hiotin. cyanocobalamin. and folic acid. Dietary deficiencies of any of the B vitamins commonly are complicated by deftciencies of another mem-ber(s) of the group,. so treatment with B-complex preparations is usually indicated. 

Most vitamins function either as a hormone/ chemical messenger (cholecalciferol), structural component in some metabolic process (pantothenic acid), or a coenzyme (phytonadi-one, thiamine, riboflavin, niacin, pyridoxine, biotin, folic acid, cyanocobalamin). At least one vitamin has more than one biochemical role. Vitamin A as an aldehyde (retinal) is a structural component of the visual pigment rhodopsin and, in its acid form (retinoic acid), is a regulator of cell differentiation. The precise biochemical functions of ascorbic acid and a-tocopherol still are not well defined. 

Ingredients Calcium Carbonate, Microcrystalline Cellulose, Magnesium Oxide, Ferrous Fumarate, Ascorbic Acid, Maltodextrin, Gelatin, dl-Alpha-Tocopheryl Acetate, Dicalcium Phosphate Less than 2% of Beta-Carotene, Biotin, Cholecalciferol, Croscarmellose Sodium, Cupric Oxide, Cyanocobalamin, D-Calcium Pantothenate, FD C Red 40 Dye, FD C Red 40 Lake, FD C Yellow 6 Lake, Folic Acid, Hydroxypropyl Methylcellulose, Niacinamide, Polyethylene Glycol, Polysorbate 80, Potassium Iodide, Pyridoxine Flydrochloride, Riboflavin, Silicon Dioxide, Soybean Oil, Starch, Stearic Acid, Thiamine Mononitrate, Titanium Dioxide (color), Vitamin A Acetate, Zinc Oxide... 

Lutavit B6. See Pyridoxine HCI Lutavit B12. See Cyanocobalamin Lutavit C Cryst. See L-Ascorbic acid Lutavit Calpan Feed Grade. See Calcium D-pantothenate... 

Vitamin Be. See Pyridoxine Vitamin B7. See L-Carnitine d-Biotin Vitamin B9. See Folic acid Vitamin B12. See Cyanocobalamin Vitamin C. See L-Ascorbic acid Vitamin D2. See Erqocalciferol Vitamin D3. See Cholecalciferol Vitamin E. See D-a-Tocopherol DL-a-Tocopherol Tocopherol Vitamin H. See d-Biotin p-Aminobenzoic acid Vitamin K CAS 12001-79-5... 

The proper functioning of the mind is known to require the presence in the brain of molecules of many different substances. For example, mental disease, usually associated with physical disease, results from a low concentration in the brain of any one of tbe following vitamins thiamine (Bi), nicotinic acid or nicotinamide (Bs), pyridoxine (Be), cyanocobalamin (Bu), biotin (H), ascorbic acid (C), and folic acid. There is evidence that mental function and behavior are also affected by changes in the concentration in the brain of any of a number of other substances that are normally present, such as L(-l-)-glutamic acid, uric acid, and y-aminobutyric acid S). 

Vitamin Bi (thiamine), B2 (riboflavin). Be (pyridoxine), B12 (cyanocobalamine), C (ascorbic acid), E (tocopherols), folic acid, pantothenic acid, K, K2, K3 (menadione), PP factor (nicotinamide), biotin Benzimidazole drugs, bromoisovalerylurea, cardiazol, chlorhexidine, dicoumarol, dulcin, isoniazid, 2-nitrofuran derivatives, parabens (4-hydroxybenzoic acid esters), phenacetin, phenylbutazone (and its metabolite oxyphenbutazone), propipocaine, quercetin, rutin, thiomersal (sodium ethylmercurithiosalicylate)... 

Thiamine, riboflavin, pantothenic acid, pyridoxine, pyridoxal, biotin, folic acid, cyanocobalamin, ascorbic acid, L-carnitine, choline, and taurine... 

The UPLC-MS/MS method has also been developed for fast simultaneous separation and determination of 14 different water-soluble vitamins and vitamin-like compounds in infant formula (thiamine, riboflavin, pantothenic acid, nicotinic acid, nicotinamide, pyridoxine, pyridoxal, biotin, fohc acid, cyanocobalamin, ascorbic acid, L-camitine, choline, and taurine) [91], Methotrexate was also used as an internal standard for riboflavin, cyanocobalamin, biotin, and folic acid, while nicotinamide was used as an internal standard for the other compounds. 

Most media contain water-soluble B vitamins. Common to many formulations are vitamins Bi (thiamine), B2 (riboflavin), B3 (niacinamide), Bj (pantothenic acid). Be (pyridoxine), and Bg (folic acid). Biotin (vitamin H), cyanocobalamin (vitamin B]2 ), and ascorbic acid (vitamin C) are also common vitamin components. Although choline and inositol are classically grouped with vitamin components, in cell culture they function as metabolic substrates rather than as catalysts. 

Prepare 5- ig/ j,l standards (Sigma) in deionized water of each of the following water-soluble vitamins thiamine-HCl cyanocobalamin (B12) riboflavin (B2) nicotinamide pyridoxine-HCl (Bj) nicotinic acid, ascorbic acid. Prepare a mixed standard containing the seven water-soluble vitamins at respective concentrations of 6, 2, 1, 6, 6, 6, 6 Xg/ 0.1. 

Draw an origin line 2 cm from the bottom of the plate and a solvent front line 15 cm from the origin. Spot 6 J.l of thiamine HCl, 2 p.1 of cyanocobalamin, 1 fil of riboflavin, 6 p.1 of nicotinamide, 6 (xl of pyridoxine-HCl, 6 pi of nicotinic acid, and 6 pi of ascorbic acid on separate origins. Spot 5 pi of the mixture on another origin. 

The following separations (approximate Rr values included) will be achieved for both individual vitamins and the mixed standard thiamine-HCl, 0.05 cyanocobalamin (B12), 0.22 riboflavin (B2), 0.40 nicotinamide, 0.49 pyridoxine-HCl (Bs), 0.52 nicotinic acid, 0.78 ascorbic acid, 0.96. The riboflavin will fluoresce yellow, whereas the other spots will appear dark. The riboflavin and pyridoxine-HCl spots may show some tailing. 

Many vitamins of medical importance can be synthesized by microorganisms. However, only two and a half vitamins are now produced by fermentation. Vitamin B2 (riboflavin) and vitamin B12 (cyanocobalamin) are products of fermentation. The remaining half vitamin produced by fermentation is vitamin C. L-Sorbose is the precursor of vitamin C (ascorbic acid), and L-sorbose is produced mirobiologically from sorbitol. 

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