Ascorbate-2-sulfate

Arylsulfatase [EC 3.1.6.1 ], also known simply as sulfatase, catalyzes the hydrolysis of a phenol sulfate, thereby producing a phenol and sulfate. This enzyme classification represents a collection of enzymes with rather similar specificities. (1) Steryl-sulfatase [EC3.1.6.2],also referred to as arylsulfatase C and steroid sulfatase, catalyzes the hydrolysis of 3-j8-hydroxyandrost-5-en-17-one 3-sulfate to 3-j8-hydroxyandrost-5-en-17-one and sulfate. The enzyme utilizes other steryl sulfates as substrates. (2) Cere-broside-sulfatase [EC 3.1.6.8], or arylsulfatase A, catalyzes the hydrolysis of a cerebroside 3-sulfate to yield a cerebroside and sulfate. The enzyme will also hydrolyze the galactose 3-sulfate bond present in a number of lipids. In addition, the enzyme will also hydrolyze ascorbate 2-sulfate and other phenol sulfates. 

This enzyme [EC 3.1.6.8], also known as arylsulfatase A, catalyzes the hydrolysis of a cerebroside 3-sulfate to produce a cerebroside and sulfate. The enzyme will also catalyze analogous reactions on the galactose 3-sulfate residues in a number of lipids as well as on ascorbate 2-sulfate and many phenol sulfates. 

Some species (but not primates) excrete ascorbate 2-sulfate, and in vitro ascorbic acid is a substrate for catechol O-methyltransferase, forming 2-methyl ascorbate. 

Attempts have been made to develop more stable forms of vitamin C for fish feeds. Ascorbate-2-sulfate has been proposed as a stable form (135) of vitamin C. As a dietary component it has been reported to cure scorbutic signs in salmonoid fish (136), to prevent scurvy in catfish... 

L-Ascorbic acid Sodium-L-ascorbate 2,3-Di-O-methylascorbic acid 3-Benzoyl ascorbate 5,6-Isopropylidene-L-ascorbic acid 3-0-[ (Dimorpholino)phosphinate]-5,6-0-isopropyli-dene-L-ascorbate Potassium-L-ascorbate 2-sulfate Cysteine HCl Cysteine free base D-Isoascorbic acid Dehydro-L-ascorbic acid... 

L-Ascorbate-2-sulfate - L-Ascorbate-2-sulfate (AAS) (14) prevented the Increase in serum lipid levels and the accumulation of cholesterol in the aorta of cholesterol-fed rabbits to a greater degree than did ascorbic acid (AA). AAS had similar effects on serum lipid levels in guinea pigs, a species which, like man, does not biosynthesize AA. It was... 

Ascorbic acid derivatives inhibit ascorbate-2-sulfate sulfohydro, dehydro-ascorbic acid. 

Potassium 3-aminopropylamide, 406 Potassium ascorbate 2-sulfate, 466 Potassium borohydride, 407 Potassium r-butoxide, 128-129, 293, 296, 407-408, 411 Potassium carbonate, 408 Potassium cyanide, 409, 453 Potassium cyanide-Acetone cyanohydrin, 409... 

Aq. 10 M NaOH-soln. added to aq. soln. of L-ascorbic acid to pH 10.0, heated to 70 , commercial SOg-trimethylamine added with periodic addition of more NaOH-soln. to maintain the pH at 9.5-10.5, and the product isolated as the Ba-salt after 0.5 hr. stirring Ba-L-ascorbate 2-sulfate dihydrate. Y 80%. F. method s. P. A. Seib et al., Soc. Perkin I 1974, 1220. 

Hatanaka, H., and Egami, F., 1976, Sulfate incorporation from ascorbate 2-sulfate into chondroitin sulfate by embryonic chick cartilage epiphyses, J. Biochem. 80 1215-1221. 

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