Ascaris suum regulation

The parasitic nematode, Ascaris suum, undergoes a number of well-characterized metabolic transitions during its development (Table 14.1), but little is known about the regulation of these events (Barrett, 1976 Komuniecki and Komuniecki, 1995). Adults reside in the porcine small intestine and fertilization takes place under low oxygen tensions. The unembryonated egg that leaves the host is metabolically quiescent, has no detectable cytochrome oxidase activity or ubiquinone and appears to be transcriptionally inactive (Cleavinger et al., 1989 Takamiya et al., 1993). Embryonation requires oxygen and after about 48-72 h is accompanied by... 

Song, H. and Komuniecki, R. (1994) Novel regulation of pyruvate dehydrogenase phosphatase purified from anaerobic muscle mitochondria of the adult parasitic nematode, Ascaris suum. Journal of Biological Chemistry 269, 31573-31578. 

Donahue, M. J., Yacoub, N. J., Kaeini, M. R. and Harris, B. G. (1981) Activity of enzymes regulating glycogen metabolism in perfused muscle-cuticle sections of Ascaris suum (Nematoda). J. Parasitol. 67 362-367. 

Merz, J. M. (1977) Short-circuit current and solute fluxes across the gut epithelium of Ascaris suum. Unpublished PhD. dissertation, Oklahoma State University, Stillwater, OK. Wright, D. J. and Newall, D. R. (1976) Osmotic and ionic regulation in nematodes. In Nematodes as Biological Models (ed. Zuckerman, B. M.), Academic Press, New York. 

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