Arginine metabolism

Wiesinger, H., Arginine metabolism and the synthesis of nitric oxide in the nervous system, Prog. Neurobiol. 64 (2001), p. 365-391... 

Ash, D.E. (2004) Arginine metabolism enzymology, nutrition and clinical significance, J. Nutr., 134,... 

The effects on nutritional indices can demonstrate an interaction between an allelochemlc and the nutritional status of the insect, but the number of actual compound-to-compound interactions that have been elucidated in Insects has been small. One of the most prominent examples is the structural analog of L-arginine, L-canavanine (see paper by G. A. Rosenthal in this symposium). Briefly, canavanlne is similar enough to arginine to be incorporated into the proteins of most insects, but these canavanyl proteins do not function properly (23). Thus, It can act as a competitive inhibitor of arginine metabolism (24, 25),... 

Mills, C. D. (1991). Molecular basis of suppressor macrophages Arginine metabolism via the nitric oxide synthetase pathway. J. Immunol. 146, 2719-2723. 

One reaction of arginine metabolism also apparently takes place in the hydrogenosomes. Arginine is a precursor in the biosynthesis of polyamines, the... 

Morris, S.M. (2002) Regulation of enzymes of the urea cycle and arginine metabolism. Annu. Rev. Nutr. 22, 87-105. 

Gensert J. M. and Ratan R. R. (2006). The metabolic coupling of arginine metabolism to nitric oxide generation by astrocytes. Antioxidants Redox Signaling 8 919-928. 

Durst, F. and Duranton, H., Effect of light on arginine metabolism in topinambour tissues cultured in vitro, Physiol. Veg., 4, 283-298, 1966. 

Mira de Orduna, R., Patchett, M.L., Liu, S.-Q., Pdone, G.l. (2001). Growth and arginine metabolism of the wine lactic acid bacteria Lactobacillus buchneri and Oenococcus oeni at different pH values and arginine concentrations. Appl. Environ. Microbiol., 67, 1657-1662. 

Pulmonary hypertension is a very different disease from the more common systemic hypertension. It occurs in people with sickle-cell disease and sometimes in newborns. Pulmonary hypertension, it now appears, involves arginine metabolism and NO availability. Arginine supplementation has been shown to improve this disease by increasing levels of the substrate for NO production. 

Minic Z, Herve G. Arginine metabolism in the deep sea tube... 

R5. Ratner, S., Morell, H., and Cervalho, E., Enzymes of arginine metabolism in brain. Arch. Biochem. Biophys. 91, 280-289 (1960). 

Schimke, R. T., Enzymes of arginine metabolism in mammalian cell culture. I. Repression of argininosuccinate synthetase and argininosuccinase. J. Biol. Chem. 239, 136-145 (1964). 

Liu, S.Q. and Pilone, G.J. (1998). A review Arginine metabolism in wine lactic acid bacteria and its pratical significance, /. Appl. Microb., 84, 315-327. 

Further investigations into hepatic arginine metabolism with regard to both the urea cycle and NO synthesis are ongoing. 

Putrescine, citrulline, and ornithine are products of arginine metabolism. The molecular formulas are given for the form in which each exists at pH = 7. The net charge corresponding to each formula is zero, +1, and +2. Suggest a reasonable structure for each species. 

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